Compounds > spirofungin b
Page last updated: 2024-11-12

spirofungin b

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

spirofungin B: isolated from Streptomyces; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID11706052
CHEMBL ID481077
SCHEMBL ID15102862
MeSH IDM0476469

Synonyms (5)

Synonym
spirofungin b
CHEMBL481077
SCHEMBL15102862
bdbm50479268
(2e,4s,5s,6e,8e)-10-[(2r,3s,6r,8r,9s)-2-[(1e,3e)-4-carboxy-3-methylbuta-1,3-dienyl]-3,9-dimethyl-1,7-dioxaspiro[5.5]undecan-8-yl]-5-hydroxy-4,8-dimethyldeca-2,6,8-trienoic acid
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (6)

Assay IDTitleYearJournalArticle
AID406779Effect on morphological reversion in src transformed NRK cells at 100 ug/mL2008Bioorganic & medicinal chemistry letters, Jul-01, Volume: 18, Issue:13
Synthesis and biological activities of reveromycin A and spirofungin A derivatives.
AID406780Effect on morphological reversion in src transformed NRK cells at 30 ug/mL2008Bioorganic & medicinal chemistry letters, Jul-01, Volume: 18, Issue:13
Synthesis and biological activities of reveromycin A and spirofungin A derivatives.
AID406778Inhibition of IleRS2008Bioorganic & medicinal chemistry letters, Jul-01, Volume: 18, Issue:13
Synthesis and biological activities of reveromycin A and spirofungin A derivatives.
AID406782Effect on morphological reversion in src transformed NRK cells at 3 ug/mL2008Bioorganic & medicinal chemistry letters, Jul-01, Volume: 18, Issue:13
Synthesis and biological activities of reveromycin A and spirofungin A derivatives.
AID406785Induction of apoptosis in mouse osteoclasts2008Bioorganic & medicinal chemistry letters, Jul-01, Volume: 18, Issue:13
Synthesis and biological activities of reveromycin A and spirofungin A derivatives.
AID406781Effect on morphological reversion in src transformed NRK cells at 10 ug/mL2008Bioorganic & medicinal chemistry letters, Jul-01, Volume: 18, Issue:13
Synthesis and biological activities of reveromycin A and spirofungin A derivatives.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (71.43)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.19

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.19 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.27 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.19)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
allyl alcohol
allyl alcohol: structure. allylic alcohol : An alcohol where the hydroxy group is attached to a saturated carbon atom adjacent to a double bond (R groups may be H, organyl, etc.).. allyl alcohol : A propenol in which the C=C bond connects C-2 and C-3. It is has been found in garlic (Allium sativum). Formerly used as a herbicide for the control of various grass and weed seeds.		2.0510primary allylic alcohol;
propenol		antibacterial agent;
fungicide;
herbicide;
insecticide;
plant metabolite
reveromycin b
reveromycin B: structure in first source		2.0410
spirofungin a
spirofungin A: isolated from Streptomyces violaceusniger; structure in first source		8.2960
ConditionIndicatedRelationship StrengthStudiesTrials