spirofungin A: isolated from Streptomyces violaceusniger; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 11848157 |
| CHEMBL ID | 456883 |
| SCHEMBL ID | 15102877 |
| MeSH ID | M0296049 |
| Synonym |
|---|
| spirofungin a |
| CHEMBL456883 |
| SCHEMBL15102877 |
| 214143-44-9 |
| bdbm50479280 |
| (2e,4s,5s,6e,8e)-10-[(2r,3s,6s,8r,9s)-2-[(1e,3e)-4-carboxy-3-methylbuta-1,3-dienyl]-3,9-dimethyl-1,7-dioxaspiro[5.5]undecan-8-yl]-5-hydroxy-4,8-dimethyldeca-2,6,8-trienoic acid |
| (2e,4s,5s,6e,8e)-10-((2r,3s,6s,8r,9s)-8-((1e,3e)-4-carboxy-3-methylbuta-1,3-dien-1-yl)-3,9-dimethyl-1,7-dioxaspiro[5.5]undecan-2-yl)-5-hydroxy-4,8-dimethyldeca-2,6,8-trienoic acid |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID406785 | Induction of apoptosis in mouse osteoclasts | 2008 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 18, Issue:13 | Synthesis and biological activities of reveromycin A and spirofungin A derivatives. |
| AID406779 | Effect on morphological reversion in src transformed NRK cells at 100 ug/mL | 2008 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 18, Issue:13 | Synthesis and biological activities of reveromycin A and spirofungin A derivatives. |
| AID406780 | Effect on morphological reversion in src transformed NRK cells at 30 ug/mL | 2008 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 18, Issue:13 | Synthesis and biological activities of reveromycin A and spirofungin A derivatives. |
| AID406782 | Effect on morphological reversion in src transformed NRK cells at 3 ug/mL | 2008 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 18, Issue:13 | Synthesis and biological activities of reveromycin A and spirofungin A derivatives. |
| AID406781 | Effect on morphological reversion in src transformed NRK cells at 10 ug/mL | 2008 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 18, Issue:13 | Synthesis and biological activities of reveromycin A and spirofungin A derivatives. |
| AID406778 | Inhibition of IleRS | 2008 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 18, Issue:13 | Synthesis and biological activities of reveromycin A and spirofungin A derivatives. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.80) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 8 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||