Page last updated: 2024-11-12
riccardin f
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
riccardin F: from Plagiochasm intermedium; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
ID Source | ID |
---|---|
PubMed CID | 11510446 |
CHEMBL ID | 474806 |
MeSH ID | M0573636 |
Synonyms (6)
Synonym |
---|
riccardin f |
riccardi f |
CHEMBL474806 |
16-methoxy-14-oxapentacyclo[20.2.2.210,13.115,19.02,7]nonacosa-1(24),2(7),3,5,10(29),11,13(28),15,17,19(27),22,25-dodecaene-5,24-diol |
98093-93-7 |
DTXSID401318218 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (10)
Assay ID | Title | Year | Journal | Article |
---|---|---|---|---|
AID602901 | Vasorelaxant activity in Wistar rat endothelium-denuded aortic rings assessed as inhibition of phenylephrine-induced contractions at 10 to 100 uM after 10 to 60 mins | 2011 | Bioorganic & medicinal chemistry, Jul-01, Volume: 19, Issue:13 | Vasorelaxant effects of macrocyclic bis(bibenzyls) from liverworts. |
AID404052 | Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells pretreated 1 hr before LPS challenge after 24 hrs by Griess reagent method | 2005 | Journal of natural products, Dec, Volume: 68, Issue:12 | Bis(bibenzyls) from liverworts inhibit lipopolysaccharide-induced inducible NOS in RAW 264.7 cells: a study of structure-activity relationships and molecular mechanism. |
AID371666 | Agonist activity at full length LXRalpha expressed in african green monkey COS7 cells co-transfected with RXRalpha assessed as increase in LXR-response element driven luciferase reporter gene transactivation at 10 to 30 uM after 24 hrs | 2009 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 19, Issue:3 | Synthesis of riccardin C and its seven analogues. Part 1: The role of their phenolic hydroxy groups as LXRalpha agonists. |
AID602900 | Vasorelaxant activity in Wistar rat endothelium-intact aortic rings assessed as inhibition of phenylephrine-induced contractions at 10 to 100 uM after 10 to 60 mins | 2011 | Bioorganic & medicinal chemistry, Jul-01, Volume: 19, Issue:13 | Vasorelaxant effects of macrocyclic bis(bibenzyls) from liverworts. |
AID1625243 | Cytotoxic activity against human A549 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay | 2019 | Journal of natural products, 04-26, Volume: 82, Issue:4 | Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia cruciata. |
AID602898 | Vasorelaxant activity in Wistar rat endothelium-intact aortic rings assessed as inhibition of phenylephrine-induced contractions after 10 to 60 mins | 2011 | Bioorganic & medicinal chemistry, Jul-01, Volume: 19, Issue:13 | Vasorelaxant effects of macrocyclic bis(bibenzyls) from liverworts. |
AID602897 | Vasorelaxant activity in Wistar rat endothelium-intact aortic rings assessed as inhibition of phenylephrine-induced contractions at 30 uM after 10 to 30 mins | 2011 | Bioorganic & medicinal chemistry, Jul-01, Volume: 19, Issue:13 | Vasorelaxant effects of macrocyclic bis(bibenzyls) from liverworts. |
AID371667 | Agonist activity at full length LXRbeta expressed in african green monkey COS7 cells co-transfected with RXRalpha assessed as increase in LXR-response element driven luciferase reporter gene transactivation at 10 to 30 uM after 24 hrs | 2009 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 19, Issue:3 | Synthesis of riccardin C and its seven analogues. Part 1: The role of their phenolic hydroxy groups as LXRalpha agonists. |
AID1625245 | Cytotoxic activity against human MRC5 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay | 2019 | Journal of natural products, 04-26, Volume: 82, Issue:4 | Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia cruciata. |
AID602899 | Vasorelaxant activity in Wistar rat endothelium-intact aortic rings assessed as inhibition of phenylephrine-induced contractions at 10 to 100 uM | 2011 | Bioorganic & medicinal chemistry, Jul-01, Volume: 19, Issue:13 | Vasorelaxant effects of macrocyclic bis(bibenzyls) from liverworts. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Research
Studies (6)
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (33.33) | 29.6817 |
2010's | 4 (66.67) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.79
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.79) All Compounds (24.57) |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 6 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |