Page last updated: 2024-11-12

riccardin f

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

riccardin F: from Plagiochasm intermedium; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID11510446
CHEMBL ID474806
MeSH IDM0573636

Synonyms (6)

Synonym
riccardin f
riccardi f
CHEMBL474806
16-methoxy-14-oxapentacyclo[20.2.2.210,13.115,19.02,7]nonacosa-1(24),2(7),3,5,10(29),11,13(28),15,17,19(27),22,25-dodecaene-5,24-diol
98093-93-7
DTXSID401318218
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (10)

Assay IDTitleYearJournalArticle
AID602901Vasorelaxant activity in Wistar rat endothelium-denuded aortic rings assessed as inhibition of phenylephrine-induced contractions at 10 to 100 uM after 10 to 60 mins2011Bioorganic & medicinal chemistry, Jul-01, Volume: 19, Issue:13
Vasorelaxant effects of macrocyclic bis(bibenzyls) from liverworts.
AID404052Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells pretreated 1 hr before LPS challenge after 24 hrs by Griess reagent method2005Journal of natural products, Dec, Volume: 68, Issue:12
Bis(bibenzyls) from liverworts inhibit lipopolysaccharide-induced inducible NOS in RAW 264.7 cells: a study of structure-activity relationships and molecular mechanism.
AID371666Agonist activity at full length LXRalpha expressed in african green monkey COS7 cells co-transfected with RXRalpha assessed as increase in LXR-response element driven luciferase reporter gene transactivation at 10 to 30 uM after 24 hrs2009Bioorganic & medicinal chemistry letters, Feb-01, Volume: 19, Issue:3
Synthesis of riccardin C and its seven analogues. Part 1: The role of their phenolic hydroxy groups as LXRalpha agonists.
AID602900Vasorelaxant activity in Wistar rat endothelium-intact aortic rings assessed as inhibition of phenylephrine-induced contractions at 10 to 100 uM after 10 to 60 mins2011Bioorganic & medicinal chemistry, Jul-01, Volume: 19, Issue:13
Vasorelaxant effects of macrocyclic bis(bibenzyls) from liverworts.
AID1625243Cytotoxic activity against human A549 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay2019Journal of natural products, 04-26, Volume: 82, Issue:4
Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia cruciata.
AID602898Vasorelaxant activity in Wistar rat endothelium-intact aortic rings assessed as inhibition of phenylephrine-induced contractions after 10 to 60 mins2011Bioorganic & medicinal chemistry, Jul-01, Volume: 19, Issue:13
Vasorelaxant effects of macrocyclic bis(bibenzyls) from liverworts.
AID602897Vasorelaxant activity in Wistar rat endothelium-intact aortic rings assessed as inhibition of phenylephrine-induced contractions at 30 uM after 10 to 30 mins2011Bioorganic & medicinal chemistry, Jul-01, Volume: 19, Issue:13
Vasorelaxant effects of macrocyclic bis(bibenzyls) from liverworts.
AID371667Agonist activity at full length LXRbeta expressed in african green monkey COS7 cells co-transfected with RXRalpha assessed as increase in LXR-response element driven luciferase reporter gene transactivation at 10 to 30 uM after 24 hrs2009Bioorganic & medicinal chemistry letters, Feb-01, Volume: 19, Issue:3
Synthesis of riccardin C and its seven analogues. Part 1: The role of their phenolic hydroxy groups as LXRalpha agonists.
AID1625245Cytotoxic activity against human MRC5 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay2019Journal of natural products, 04-26, Volume: 82, Issue:4
Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia cruciata.
AID602899Vasorelaxant activity in Wistar rat endothelium-intact aortic rings assessed as inhibition of phenylephrine-induced contractions at 10 to 100 uM2011Bioorganic & medicinal chemistry, Jul-01, Volume: 19, Issue:13
Vasorelaxant effects of macrocyclic bis(bibenzyls) from liverworts.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's4 (66.67)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.79

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.79 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.73 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.79)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]