rapalexin a

Description

rapalexin A: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Synonym
929083-72-7
CHEMBL2253033
rapalexin a
3-isothiocyanato-4-methoxy-1h-indole
DTXSID70582863
SCHEMBL19400912

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Assay ID	Title	Year	Journal	Article
AID1092145	Antifungal activity against Leptosphaeria maculans assessed as mycelial radial growth inhibition on potato dextrose agar at 0.50 mM relative to control	2012	Bioorganic & medicinal chemistry, Jul-01, Volume: 20, Issue:13	The cruciferous phytoalexins rapalexin A, brussalexin A and erucalexin: chemistry and metabolism in Leptosphaeria maculans.
AID1092143	Antifungal activity against Leptosphaeria maculans assessed as mycelial radial growth inhibition on potato dextrose agar at 0.10 mM relative to control	2012	Bioorganic & medicinal chemistry, Jul-01, Volume: 20, Issue:13	The cruciferous phytoalexins rapalexin A, brussalexin A and erucalexin: chemistry and metabolism in Leptosphaeria maculans.
AID1092144	Antifungal activity against Leptosphaeria maculans assessed as mycelial radial growth inhibition on potato dextrose agar at 0.20 mM relative to control	2012	Bioorganic & medicinal chemistry, Jul-01, Volume: 20, Issue:13	The cruciferous phytoalexins rapalexin A, brussalexin A and erucalexin: chemistry and metabolism in Leptosphaeria maculans.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (28.57)	29.6817
2010's	4 (57.14)	24.3611
2020's	1 (14.29)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	7 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
indole-3-carbinol indole-3-carbinol: occurs in edible cruciferous vegetables. indole-3-methanol : An indolyl alcohol carrying a hydroxymethyl group at position 3. It is a constituent of the cruciferous vegetables and had anticancer activity.	2.07	1	indolyl alcohol	antineoplastic agent; plant metabolite
thiazoles [no description available]	2.46	2	1,3-thiazoles; mancude organic heteromonocyclic parent; monocyclic heteroarene
camalexin camalexin : An indole phytoalexin that is indole substituted at position 3 by a 1,3-thiazol-2-yl group.	7.04	1	1,3-thiazoles; indole phytoalexin	metabolite
sesquiterpenes [no description available]	3.17	5
cysteine Cysteine: A thiol-containing non-essential amino acid that is oxidized to form CYSTINE.. L-cysteinium : The L-enantiomer of cysteinium.. cysteine : A sulfur-containing amino acid that is propanoic acid with an amino group at position 2 and a sulfanyl group at position 3.	7.25	1	cysteinium	fundamental metabolite
wasalexin a wasalexin A: wasalexins A and B are geometrical isomers; isolated from Wasabia japonica; structure in first source	2.04	1	indoles