| Assay ID | Title | Year | Journal | Article |
|---|
| AID1192444 | Inhibition of TGF-beta-induced human CTGF promoter activity transiently transfected in human HepG2 cells assessed as reduction in tgf-beta expression preincubated at 680 nM for 1 hr before TGF-beta stimulation measured after 6 hrs by quantitative real-tim | 2015 | Bioorganic & medicinal chemistry, Feb-01, Volume: 23, Issue:3
| 4-Dechloro-14-deoxy-oxacyclododecindione and 14-deoxy-oxacylododecindione, two inhibitors of inducible connective tissue growth factor expression from the imperfect fungus Exserohilum rostratum. |
| AID1192445 | Inhibition of TGF-beta-induced human CTGF promoter activity transiently transfected in human HepG2 cells assessed as reduction in plasminogen activator inhibitor-1 expression preincubated at 680 nM for 1 hr before TGF-beta stimulation measured after 6 hrs | 2015 | Bioorganic & medicinal chemistry, Feb-01, Volume: 23, Issue:3
| 4-Dechloro-14-deoxy-oxacyclododecindione and 14-deoxy-oxacylododecindione, two inhibitors of inducible connective tissue growth factor expression from the imperfect fungus Exserohilum rostratum. |
| AID1192441 | Binding affinity to (AGCCAGACA)9-MLP element (unknown origin) transiently transfected in human HepG2 cells assessed as inhibition of TGF-beta-induced Smad-dependent transcriptional activity preincubated for 1 hr before TGF-beta stimulation measured after | 2015 | Bioorganic & medicinal chemistry, Feb-01, Volume: 23, Issue:3
| 4-Dechloro-14-deoxy-oxacyclododecindione and 14-deoxy-oxacylododecindione, two inhibitors of inducible connective tissue growth factor expression from the imperfect fungus Exserohilum rostratum. |
| AID1192436 | Inhibition of TGF-beta-induced human CTGF promoter activity transiently transfected in human HepG2 cells assessed as CTGF protein expression preincubated at 407 nM for 1 hr before TGF-beta stimulation measured after 8 hrs by Western blot analysis | 2015 | Bioorganic & medicinal chemistry, Feb-01, Volume: 23, Issue:3
| 4-Dechloro-14-deoxy-oxacyclododecindione and 14-deoxy-oxacylododecindione, two inhibitors of inducible connective tissue growth factor expression from the imperfect fungus Exserohilum rostratum. |
| AID1192464 | Antimigratory activity against human MDA-MB-231 cells assessed as reduction in formation of tubule-like structures after 16 hrs by matrigel assay relative to control | 2015 | Bioorganic & medicinal chemistry, Feb-01, Volume: 23, Issue:3
| 4-Dechloro-14-deoxy-oxacyclododecindione and 14-deoxy-oxacylododecindione, two inhibitors of inducible connective tissue growth factor expression from the imperfect fungus Exserohilum rostratum. |
| AID1192440 | Inhibition of TGF-beta-induced human CTGF promoter activity transiently transfected in human HepG2 cells assessed as reduction in alpha-smooth muscle actin expression preincubated at 680 nM for 1 hr before TGF-beta stimulation measured after 6 hrs by quan | 2015 | Bioorganic & medicinal chemistry, Feb-01, Volume: 23, Issue:3
| 4-Dechloro-14-deoxy-oxacyclododecindione and 14-deoxy-oxacylododecindione, two inhibitors of inducible connective tissue growth factor expression from the imperfect fungus Exserohilum rostratum. |
| AID1192433 | Inhibition of TGF-beta-induced human CTGF promoter activity transiently transfected in human HepG2 cells assessed as CTGF expression preincubated at 680 nM for 1 hr before TGF-beta stimulation measured after 4 hrs by quantitative real-time PCR analysis | 2015 | Bioorganic & medicinal chemistry, Feb-01, Volume: 23, Issue:3
| 4-Dechloro-14-deoxy-oxacyclododecindione and 14-deoxy-oxacylododecindione, two inhibitors of inducible connective tissue growth factor expression from the imperfect fungus Exserohilum rostratum. |
| AID1192432 | Inhibition of TGF-beta-induced human CTGF promoter activity transiently transfected in human HepG2 cells after 16 hrs by luciferase reporter assay | 2015 | Bioorganic & medicinal chemistry, Feb-01, Volume: 23, Issue:3
| 4-Dechloro-14-deoxy-oxacyclododecindione and 14-deoxy-oxacylododecindione, two inhibitors of inducible connective tissue growth factor expression from the imperfect fungus Exserohilum rostratum. |
| AID1192439 | Inhibition of TGF-beta-induced human CTGF promoter activity transiently transfected in human HepG2 cells assessed as reduction in type 1 collagen alpha1 expression preincubated at 680 nM for 1 hr before TGF-beta stimulation measured after 6 hrs by quantit | 2015 | Bioorganic & medicinal chemistry, Feb-01, Volume: 23, Issue:3
| 4-Dechloro-14-deoxy-oxacyclododecindione and 14-deoxy-oxacylododecindione, two inhibitors of inducible connective tissue growth factor expression from the imperfect fungus Exserohilum rostratum. |
| AID1192443 | Inhibition of TGF-beta-induced human CTGF promoter activity transiently transfected in human HepG2 cells assessed as reduction in mmp2 expression preincubated at 680 nM for 1 hr before TGF-beta stimulation measured after 6 hrs by quantitative real-time PC | 2015 | Bioorganic & medicinal chemistry, Feb-01, Volume: 23, Issue:3
| 4-Dechloro-14-deoxy-oxacyclododecindione and 14-deoxy-oxacylododecindione, two inhibitors of inducible connective tissue growth factor expression from the imperfect fungus Exserohilum rostratum. |
| AID1192459 | Antimigratory activity against human MDA-MB-231 cells assessed as reduction in formation of tubule-like structures at 136 nM after 16 hrs by matrigel assay relative to control | 2015 | Bioorganic & medicinal chemistry, Feb-01, Volume: 23, Issue:3
| 4-Dechloro-14-deoxy-oxacyclododecindione and 14-deoxy-oxacylododecindione, two inhibitors of inducible connective tissue growth factor expression from the imperfect fungus Exserohilum rostratum. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |