Compounds > opc-2009
Page last updated: 2024-09-28

opc-2009

Cross-References

ID SourceID
PubMed CID656601
CHEMBL ID1322218
CHEBI ID32056
SCHEMBL ID124726
MeSH IDM0026204

Synonyms (18)

Synonym
AC-4219
opc-2009
procaterol hydrochloride (usan)
D02404
pro-air (tn)
MLS000028683
smr000058864
chebi:32056 ,
CHEMBL1322218
AKOS015967634
CCG-39328
FT-0630887
FT-0630735
SCHEMBL124726
5-(1-hydroxy-2-isopropylaminobutyl)-8-hydroxycarbostyril hydrochloride
AEQDBKHAAWUCMT-UHFFFAOYSA-N
8-hydroxy-5-(1-hydroxy-2-(isopropylamino)butyl)quinolin-2(1h)-one hydrochloride
Q27114767

Drug Classes (1)

ClassDescription
organic molecular entityAny molecular entity that contains carbon.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (17)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASEHomo sapiens (human)Potency35.48130.003245.467312,589.2998AID2517
Chain A, JmjC domain-containing histone demethylation protein 3AHomo sapiens (human)Potency39.81070.631035.7641100.0000AID504339
Chain A, 2-oxoglutarate OxygenaseHomo sapiens (human)Potency35.48130.177814.390939.8107AID2147
Chain A, Ferritin light chainEquus caballus (horse)Potency31.62285.623417.292931.6228AID485281
Smad3Homo sapiens (human)Potency0.10000.00527.809829.0929AID588855
apical membrane antigen 1, AMA1Plasmodium falciparum 3D7Potency7.94330.707912.194339.8107AID720542
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)Homo sapiens (human)Potency2.51190.00137.762544.6684AID914; AID915
euchromatic histone-lysine N-methyltransferase 2Homo sapiens (human)Potency44.66840.035520.977089.1251AID504332
beta-2 adrenergic receptorHomo sapiens (human)Potency0.06860.00586.026332.6427AID492947; AID588463; AID588790
lysosomal alpha-glucosidase preproproteinHomo sapiens (human)Potency6.30960.036619.637650.1187AID2100
importin subunit beta-1 isoform 1Homo sapiens (human)Potency89.12515.804836.130665.1308AID540263
flap endonuclease 1Homo sapiens (human)Potency17.78280.133725.412989.1251AID588795
snurportin-1Homo sapiens (human)Potency89.12515.804836.130665.1308AID540263
DNA polymerase iota isoform a (long)Homo sapiens (human)Potency15.84890.050127.073689.1251AID588590
gemininHomo sapiens (human)Potency0.20600.004611.374133.4983AID624297
survival motor neuron protein isoform dHomo sapiens (human)Potency2.51190.125912.234435.4813AID1458
D(3) dopamine receptor isoform eHomo sapiens (human)Potency3.16230.02009.148539.8107AID720506
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (13)

Assay IDTitleYearJournalArticle
AID651635Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression
AID1745845Primary qHTS for Inhibitors of ATXN expression
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID504810Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID504812Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
Acetylpheneturide[no description available]low00organic molecular entity
afloqualone[no description available]low00organic molecular entity
aranidipine[no description available]low00organic molecular entity
bromazepam[no description available]low00organic molecular entity
seratrodast[no description available]low00organic molecular entity
brotizolam[no description available]low00organic molecular entity
cadralazine[no description available]low00organic molecular entity
carbazilquinone[no description available]low00organic molecular entity
clinofibrate[no description available]low00organic molecular entity
clotiazepam[no description available]low00organic molecular entity
cyclofenil[no description available]low00organic molecular entity
ebastine[no description available]low00organic molecular entity
emorfazone[no description available]low00organic molecular entity
ethenzamide[no description available]low00organic molecular entity
ethyl loflazepate[no description available]low00organic molecular entity
etizolam[no description available]low00organic molecular entity
amidoline[no description available]low00organic molecular entity
floctafenine[no description available]low00organic molecular entity
flopropione[no description available]low00organic molecular entity
fp 83[no description available]low00organic molecular entity
flutazolam[no description available]low00hemiaminal ether;
organic molecular entity
flutoprazepam[no description available]low00organic molecular entity
glybuzole[no description available]low00organic molecular entity
haloxazolam[no description available]low00organic molecular entity
ibuprofen piconol[no description available]low00organic molecular entity
iothalamic acid[no description available]low00organic molecular entity
iotrolan[no description available]low00organic molecular entity
iotroxic acid[no description available]low00organic molecular entity
mazindol[no description available]low00organic molecular entity
medazepam[no description available]low00organic molecular entity
mefruside[no description available]low00organic molecular entity
meprobamate[no description available]low00organic molecular entity
metharbital[no description available]low00organic molecular entity
methyprylon[no description available]low00organic molecular entity
myristicin[no description available]low00organic molecular entitymetabolite
niceritrol[no description available]low00organic molecular entity
osalmide[no description available]low00organic molecular entity
oxazolam[no description available]low00hemiaminal ether;
organic molecular entity
oxypertine[no description available]low00organic molecular entity
pirenoxine[no description available]low00organic molecular entity
propyliodone[no description available]low00organic molecular entity
repirinast[no description available]low00organic molecular entity
simfibrate[no description available]low00organic molecular entity
sobuzoxane[no description available]low00organic molecular entity
sulthiame[no description available]low00organic molecular entity
tazanolast[no description available]low00organic molecular entity
tofisopam[no description available]low00organic molecular entity
3-(2',4',5'-triethoxybenzoyl)propionic acid[no description available]low00organic molecular entity
vesnarinone[no description available]low00organic molecular entity
cn 100[no description available]low00organic molecular entity
procaine hydrochloride[no description available]low00organic molecular entity
lysine[no description available]low00aspartate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
lysine;
organic molecular entity;
proteinogenic amino acid		algal metabolite;
anticonvulsant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
Mebutamate[no description available]low00organic molecular entity
methandrostenolone[no description available]low00organic molecular entity
tetramethylammonium chloride[no description available]low00organic molecular entity
methsuximide[no description available]low00organic molecular entity
1-phenylpropanol[no description available]low00organic molecular entity
butylparaben[no description available]low00organic molecular entity
efloxate[no description available]low00organic molecular entity
sulfan blue[no description available]low00organic molecular entity
1,2-dihydroxybenzene-3,5-disulfonic acid disodium salt[no description available]low00organic molecular entity
cycloguanil hydrochloride[no description available]low00hydrochloride;
organic molecular entity
nicarbazin[no description available]low00organic molecular entity
fluocinonide[no description available]low00organic molecular entity
copper gluconate[no description available]low00organic molecular entity
naphazoline hydrochloride[no description available]low00organic molecular entity
doxylamine succinate[no description available]low00organic molecular entity
carbamylhydrazine monohydrochloride[no description available]low00organic molecular entity
Berberine chloride (TN)[no description available]low00organic molecular entity
isosorbide[no description available]low00organic molecular entity
bucetin[no description available]low00organic molecular entity
tetradecyltrimethylammonium bromide[no description available]low00organic molecular entity
rimantadine hydrochloride[no description available]low00organic molecular entity
nitrofen[no description available]low00organic molecular entityEC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide
perlapine[no description available]low00organic molecular entity
clorexolone[no description available]low00organic molecular entity
stavudine[no description available]low00dihydrofuran;
nucleoside analogue;
organic molecular entity		antimetabolite;
antiviral agent;
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
iobenzamic acid[no description available]low00organic molecular entity
sulfamethomidine[no description available]low00organic molecular entity
Brilliant Blue[no description available]low00organic molecular entity
pyrodifenium bromide[no description available]low00organic molecular entity
didecyldimethylammonium chloride[no description available]low00organic molecular entity
iocarmic acid[no description available]low00organic molecular entity
bisoxatin acetate[no description available]low00organic molecular entity
levamisole hydrochloride[no description available]low00organic molecular entity
halazepam[no description available]low00organic molecular entity
nicomol[no description available]low00organic molecular entity
feprazone[no description available]low00organic molecular entity
b 10610[no description available]low00organic molecular entity
haloperidol decanoate[no description available]low00organic molecular entity
pinacidil[no description available]low00organic molecular entity
loxiglumide[no description available]low00organic molecular entity
saquinavir monomethanesulfonate[no description available]low00organic molecular entity
Pronetalol hydrochloride[no description available]low00organic molecular entity
phenelzine sulfate[no description available]low00organic molecular entity
magnesium peroxide[no description available]low00organic molecular entity
dexamethasone 21-palmitate[no description available]low00organic molecular entity
rotenolone[no description available]low00organic molecular entitymetabolite
nilverm[no description available]low00organic molecular entity
diumide[no description available]low00organic molecular entity
docarpamine[no description available]low00organic molecular entity
clobetasone butyrate[no description available]low00organic molecular entity
enocitabine[no description available]low00organic molecular entity
ranimustine[no description available]low00organic molecular entity
protizinic acid[no description available]low00organic molecular entity
nipradilol[no description available]low00organic molecular entity
panipenem[no description available]low00organic molecular entity
p-Aminobenzamidine dihydrochloride[no description available]low00organic molecular entity
aucubin[no description available]low00organic molecular entitymetabolite
catalpol[no description available]low00organic molecular entitymetabolite
halopredone acetate[no description available]low00organic molecular entity
3-acetyllupeol[no description available]low00organic molecular entitymetabolite
phenmetrazine hydrochloride[no description available]low00organic molecular entity
isometamidium chloride[no description available]low00organic molecular entity
melanotan-ii[no description available]low00organic molecular entity
anecortave acetate[no description available]low00organic molecular entity
aluminum phthalocyanine[no description available]low00organic molecular entity
olprinone[no description available]low00organic molecular entity
clidanac[no description available]low00organic molecular entity
enkephalin-met, arg(6)-phe(7)-[no description available]low00organic molecular entity
angiotensin ii, des-asp(1)-des-arg(2)-ile(5)-[no description available]low00organic molecular entity
ramatroban[no description available]low00organic molecular entity
3-acetylpyridine adenine dinucleotide[no description available]low00organic molecular entity
iguratimod[no description available]low00organic molecular entity
blonanserin[no description available]low00organic molecular entity
fudosteine[no description available]low00organic molecular entity
perlolyrine[no description available]low00organic molecular entitymetabolite
timepidium bromide[no description available]low00organic molecular entity
2-(2-hydroxy-4-methylphenyl)aminothiazole[no description available]low00organic molecular entity
cupric hydroxide[no description available]low00organic molecular entity
beta-mercaptolactate cysteine disulfide[no description available]low00organic molecular entity
s 8308[no description available]low00organic molecular entity
farrerol[no description available]low00organic molecular entitymetabolite
hydroxylamine hydrochloride[no description available]low00organic molecular entity
cyclo(l-phe-l-pro)[no description available]low00organic molecular entitymetabolite
gestonorone caproate[no description available]low00organic molecular entity
epitiostanol[no description available]low00organic molecular entity
halcinonide[no description available]low00organic molecular entitySMO receptor agonist
oxendolone[no description available]low00organic molecular entity
dironyl[no description available]low00organic molecular entity
ao 128[no description available]low00organic molecular entity
ditiocarb sodium[no description available]low00organic molecular entity
aceglatone[no description available]low00organic molecular entity
bucillamine[no description available]low00organic molecular entity
cefsulodin sodium[no description available]low00organic molecular entity
n-(3,4-dimethoxyphenyl)-n-(3-((2-(3,4-dimethoxyphenyl)ethyl)methylamino)propyl)-4-nitrobenzamide hydrochloride[no description available]low00organic molecular entity
4E2RCat[no description available]low00organic molecular entity
potassium oxonate[no description available]low00organic molecular entity
p-aminosalicylic acid monosodium salt[no description available]low00organic molecular entity
1-deoxyfructose[no description available]low00organic molecular entity
ungeremine[no description available]low00organic molecular entitymetabolite
ethyl 4-(3-oxo-2,3-dihydroisothiazol-2-yl)benzoate[no description available]low00organic molecular entity
pyrantel pamoate[no description available]low00organic molecular entity
chlorpheniramine maleate[no description available]low00organic molecular entity
dexchlorpheniramine maleate[no description available]low00organic molecular entity
gsh-prostaglandin a1[no description available]low00organic molecular entity
lafutidine[no description available]low00organic molecular entity
pheniramine maleate[no description available]low00organic molecular entity
sf 837[no description available]low00organic molecular entity
gefarnate[no description available]low00organic molecular entity
sorivudine[no description available]low00organic molecular entity
ornoprostil[no description available]low00organic molecular entity
cd 3400[no description available]low00organic molecular entity
rokitamycin[no description available]low00organic molecular entity
prednisolone farnesylate[no description available]low00organic molecular entity
dinoprost tromethamine[no description available]low00organic molecular entity
phenoxybenzamine hydrochloride[no description available]low00organic molecular entity
proscillaridin[no description available]low00organic molecular entity
goserelin[no description available]low00organic molecular entity
azodicarbonamide[no description available]low00organic molecular entity
tulobuterol hydrochloride[no description available]low00organic molecular entity
maxacalcitol[no description available]low00organic molecular entity
longiborneol[no description available]low00organic molecular entity
falcarindiol[no description available]low00organic molecular entitymetabolite
ozagrel, monohydrochloride, (e)-isomer[no description available]low00organic molecular entity
microcystin rr[no description available]low00microcystin;
organic molecular entity		bacterial metabolite;
environmental contaminant;
xenobiotic
lankacidins[no description available]low00organic molecular entity
romurtide[no description available]low00organic molecular entity
ciclesonide[no description available]low00organic molecular entity
fursultiamin monohydrochloride[no description available]low00organic molecular entity
pentagastrin[no description available]low00organic molecular entity
mepitiostane[no description available]low00organic molecular entity
calcium sulfide[no description available]low00organic molecular entity
barettin[no description available]low00organic molecular entity
8-hydroxy-2-(di-n-propylamino)tetralin hydrobromide, (r)-isomer,[no description available]low00organic molecular entity
nociceptin[no description available]low00organic molecular entity;
polypeptide		human metabolite;
rat metabolite
sodium salicylate[no description available]low00organic molecular entity
n-(2-methylbenzyl)linoleamide[no description available]low00organic molecular entity
halisulfate 1[no description available]low00organic molecular entitymetabolite
novobiocin sodium[no description available]low00organic molecular entity
cefoperazone sodium[no description available]low00organic molecular entity
osteum[no description available]low00organic molecular entity
cefoxitin sodium[no description available]low00organic molecular entity
dexon (fungicide), sodium salt[no description available]low00organic molecular entity
zinacef[no description available]low00organic molecular entity
sodium iodate[no description available]low00organic molecular entity
pyrithiobac sodium[no description available]low00organic molecular entity
cortisol succinate, sodium salt[no description available]low00organic molecular entity
sodium 2,6-dichloroindophenol[no description available]low00organic molecular entity
quinupristin-dalfopristin[no description available]low00organic molecular entity
gyy 4137[no description available]low00organic molecular entity
monanchocidin[no description available]low00organic molecular entitymetabolite
spinetoram[no description available]low00organic molecular entity
gimeracil[no description available]low00organic molecular entity
suvanine[no description available]low00organic molecular entitymetabolite
vt-1161[no description available]low00organic molecular entity
3-hydroxykynurenine glucoside[no description available]low00organic molecular entity
dBET6[no description available]low00organic molecular entity
MZ1[no description available]low00organic molecular entity
staphylopine(1-)[no description available]low00organic molecular entity
pseudopaline(2-)[no description available]low00organic molecular entity
valtrex[no description available]low00organic molecular entity
hlo 7[no description available]low00organic molecular entity
7-deazaguanine[no description available]low00organic molecular entity
7,8-dihydropterin[no description available]low00organic molecular entity;
pterins
pteroylpentaglutamic acid[no description available]low00organic molecular entity
amicoumacin a[no description available]low00organic molecular entity
ConditionIndicatedRelationship StrengthStudiesTrials
Inflammation0low10
Innate Inflammatory Response0low10