nafuredin: inhibits fumarate reductase (NADH); structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 10338591 |
| CHEMBL ID | 4162866 |
| MeSH ID | M0383920 |
| Synonym |
|---|
| nafuredin |
| 224427-79-6 |
| (1r,2r,5r,6s)-5-hydroxy-1-methyl-2-[(1e,3e,5r,7e,9e,11s)-5,7,11-trimethyltrideca-1,3,7,9-tetraenyl]-3,7-dioxabicyclo[4.1.0]heptan-4-one |
| (+)-nafuredin |
| (1r,2r,5r,6s)-5-hydroxy-1-methyl-2-((1e,3e,5r,7e,9e,11s)-5,7,11-trimethyl-1,3,7,9-tridecatetraen-1-yl)-3,7-dioxabicyclo(4.1.0)heptan-4-one |
| unii-4j6nv9s26k |
| 3,7-dioxabicyclo(4.1.0)heptan-4-one, 5-hydroxy-1-methyl-2-((1e,3e,5r,7e,9e,11s)-5,7,11-trimethyl-1,3,7,9-tridecatetraen-1-yl)-, (1r,2r,5r,6s)- |
| 4j6nv9s26k , |
| 3,7-dioxabicyclo(4.1.0)heptan-4-one, 5-hydroxy-1-methyl-2-((1e,3e,5r,7e,9e,11s)-5,7,11-trimethyl-1,3,7,9-tridecatetraenyl)-, (1r,2r,5r,6s)- |
| ft-0554 |
| CHEMBL4162866 |
| Pathway | Proteins | Compounds |
|---|---|---|
| anaerobic energy metabolism (invertebrates, mitochondrial) | 13 | 42 |
| superpathway of anaerobic energy metabolism (invertebrates) | 16 | 60 |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1504527 | Cytotoxicity against human HeLa cells by SRB method | 2017 | Journal of natural products, 12-22, Volume: 80, Issue:12 | Inducing Secondary Metabolite Production by Combined Culture of Talaromyces aculeatus and Penicillium variabile. |
| AID1504528 | Cytotoxicity against human K562 cells by MTT method | 2017 | Journal of natural products, 12-22, Volume: 80, Issue:12 | Inducing Secondary Metabolite Production by Combined Culture of Talaromyces aculeatus and Penicillium variabile. |
| AID1504532 | Cytotoxicity against human MCF7 cells by SRB method | 2017 | Journal of natural products, 12-22, Volume: 80, Issue:12 | Inducing Secondary Metabolite Production by Combined Culture of Talaromyces aculeatus and Penicillium variabile. |
| AID1504529 | Cytotoxicity against human HCT116 cells by SRB method | 2017 | Journal of natural products, 12-22, Volume: 80, Issue:12 | Inducing Secondary Metabolite Production by Combined Culture of Talaromyces aculeatus and Penicillium variabile. |
| AID1504530 | Cytotoxicity against human HL60 cells by MTT method | 2017 | Journal of natural products, 12-22, Volume: 80, Issue:12 | Inducing Secondary Metabolite Production by Combined Culture of Talaromyces aculeatus and Penicillium variabile. |
| AID1504531 | Cytotoxicity against human A549 cells by SRB method | 2017 | Journal of natural products, 12-22, Volume: 80, Issue:12 | Inducing Secondary Metabolite Production by Combined Culture of Talaromyces aculeatus and Penicillium variabile. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 10 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||