Page last updated: 2024-10-06

superpathway of anaerobic energy metabolism (invertebrates)

Proteins (16)

ProteinSynonymsTaxonomy
Pyruvate dehydrogenase E1 component subunit alpha type I, mitochondrialPDHA1; PDHE1-A; EC 1.2.4.1Ascaris suum (pig roundworm)
Pyruvate dehydrogenase E1 component subunit beta, mitochondrialPDHE1-B; EC 1.2.4.1Ascaris suum (pig roundworm)
NAD-dependent malic enzyme, mitochondrialNAD-ME; EC 1.1.1.38Ascaris suum (pig roundworm)
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Ascaris suum (pig roundworm)
Phosphoenolpyruvate carboxykinase [GTP]PEPCK; EC 4.1.1.32Ascaris suum (pig roundworm)
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Ascaris suum (pig roundworm)
Methylmalonyl-CoA mutase Ascaris suum (pig roundworm)
Pyruvate kinase Crassostrea gigas (Pacific oyster)
Malate dehydrogenase Mytilus trossulus (common blue mussel)
Fumarate hydratase Ascaris suum (pig roundworm)
Dihydrolipoyl dehydrogenase Ascaris suum (pig roundworm)
Acetyl-CoA deacylase Fasciola hepatica (liver fluke)
Acetyltransferase component of pyruvate dehydrogenase complex Ascaris suum (pig roundworm)
Dihydrolipoyl dehydrogenase-binding proteinAscaris suum (pig roundworm)
Succinate dehydrogenase cytochrome b560 subunit, mitochondrialAscaris suum (pig roundworm)
Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrialCybS; Cytochrome b558 small subunit; Succinate-ubiquinone reductase membrane anchor subunitAscaris suum (pig roundworm)

Compounds (40)

CompoundDescription
hydronium ion
CobaltA trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis.
Succinate
NADH
CalciumA basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
ManganeseA trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
Orthophosphate
Aspartate
fumaratesCompounds based on fumaric acid.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
hydrogen carbonate
potassiumAn element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE.
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
SodiumA member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
succinyl-coenzyme A
cobamamide
atpenin a5from Penicillium sp. FO-125; MW C15-H21-N-O5-Cl2
nafuredininhibits fumarate reductase (NADH); structure in first source
Pyruvic AcidAn intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
alpha-Ketoglutarate
OxaloacetateAn anionic form of oxaloacetic acid.
diethyl pyrocarbonatePreservative for wines, soft drinks, and fruit juices and a gentle esterifying agent.
CadmiumAn element with atomic symbol Cd, atomic number 48, and atomic weight 112.41. It is a metal and ingestion will lead to CADMIUM POISONING.
ethylmaleimideA sulfhydryl reagent that is widely used in experimental biochemical studies.
glutamate
fructose-1,6-diphosphateRN refers to (D)-isomer
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
diacetylCarrier of aroma of butter, vinegar, coffee, and other foods.
cyclic ampAn adenine nucleotide containing one phosphate group which is esterified to both the 3'- and 5'-positions of the sugar moiety. It is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones, including epinephrine, glucagon, and ACTH.
4,4'-dipyridyl disulfide
hydroxylamineA colorless inorganic compound (HONH2) used in organic synthesis and as a reducing agent, due to its ability to donate nitric oxide.
Coenzyme A
Acetyl Coenzyme AAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.
propionyl-coenzyme ARN given refers to parent cpd
Flavin-Adenine DinucleotideA condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972)
flutolanil
phenylhydrazineRN given refers to parent cpd