Page last updated: 2024-12-08

kp 136

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

KP 136: RN given refers to parent cpd [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	166484
SCHEMBL ID	6439140
SCHEMBL ID	15660386
MeSH ID	M0150420

Synonyms (18)

Synonym
al-136
kp-136
kp 136
al 136
2h-1-benzopyran-2-one, 8-(hexyloxy)-3-(1h-tetrazol-5-yl)-
8-n-hexyloxy-3-(1h-tetrazol-5-yl)coumarin
8-(hexyloxy)-3-(1h-tetrazol-5-yl)-2h-1-benzopyran-2-one
76239-32-2
8-hexoxy-3-(2h-tetrazol-5-yl)chromen-2-one
2h-1-benzopyran-2-one,8-(hexyloxy)-3-(2h-tetrazol-5-yl)-
DTXSID90227087
al136 ,
SCHEMBL6439140
SCHEMBL15660386
CS-7226
kp136
HY-U00168
AKOS040741917

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	4 (80.00)	18.7374
1990's	1 (20.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.51

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	12.51 (24.57)
Research Supply Index	1.79 (2.92)
Research Growth Index	4.31 (4.65)
Search Engine Demand Index	0.00 (26.88)
Search Engine Supply Index	0.00 (0.95)

This Compound (12.51)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	5 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
histamine [no description available]	1.97	1	aralkylamino compound; imidazoles	human metabolite; mouse metabolite; neurotransmitter
cromolyn sodium Cromolyn Sodium: A chromone complex that acts by inhibiting the release of chemical mediators from sensitized MAST CELLS. It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack.. disodium cromoglycate : An organic sodium salt that is the disodium salt of cromoglycic acid.	2.66	3	organic sodium salt	anti-asthmatic drug; drug allergen
calcimycin Calcimycin: An ionophorous, polyether antibiotic from Streptomyces chartreusensis. It binds and transports CALCIUM and other divalent cations across membranes and uncouples oxidative phosphorylation while inhibiting ATPase of rat liver mitochondria. The substance is used mostly as a biochemical tool to study the role of divalent cations in various biological systems.	1.97	1	benzoxazole

Condition	Relationship Strength	Studies
Polyarthritis [description not available]	1.97	1
Adjuvant Arthritis [description not available]	1.97	1
Arthus Phenomenon [description not available]	1.97	1
Anasarca [description not available]	1.97	1
Extravascular Hemolysis [description not available]	2.38	2
Delayed Hypersensitivity [description not available]	1.97	1
Atopic Hypersensitivity [description not available]	1.97	1
Arthritis Acute or chronic inflammation of JOINTS.	1.97	1
Edema Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.	1.97	1
Hemolysis The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.	2.38	2
Asthma, Bronchial [description not available]	2.38	2
Asthma A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).	2.38	2
Muscle Relaxation That phase of a muscle twitch during which a muscle returns to a resting position.	1.97	1
Allergic Reaction [description not available]	1.97	1
Hypersensitivity Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.	1.97	1

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