khusimol: a non-peptide molecule isolated from Vetiveria zizanioides; a sesquiterpene alcohol; inhibits the binding of vasopressin to rat liver vasopressin V(1a) receptors; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| Flora | Rank | Flora Definition | Family | Family Definition |
|---|---|---|---|---|
| Vetiveria | genus | [no description available] | Poaceae | A large family of narrow-leaved herbaceous grasses of the order Cyperales, subclass Commelinidae, class Liliopsida (monocotyledons). Food grains (EDIBLE GRAIN) come from members of this family. RHINITIS, ALLERGIC, SEASONAL can be induced by POLLEN of many of the grasses.[MeSH] |
| ID Source | ID |
|---|---|
| PubMed CID | 167519 |
| CHEMBL ID | 511334 |
| SCHEMBL ID | 16982577 |
| MeSH ID | M0241137 |
| Synonym |
|---|
| khusimol |
| bdbm50292418 |
| CHEMBL511334 , |
| 16223-63-5 |
| unii-t4n33ecg0w |
| t4n33ecg0w , |
| 1h-3a,6-methanoazulene-3-methanol, octahydro-7,7-dimethyl-8-methylene-, (3s-(3alpha,3aalpha,6alpha,8aalpha))- |
| 1h-3a,6-methanoazulene-3-methanol, octahydro-7,7-dimethyl-8-methylene-, (3s-(3.alpha.,3a.alpha.,6.alpha.,8a.alpha.))- |
| 1h-3a,6-methanoazulene-3-methanol, octahydro-7,7-dimethyl-8-methylene-, (3s,3ar,6r,8as)- |
| SCHEMBL16982577 |
| DTXSID80936671 |
| [(1r,2s,5s,8r)-7,7-dimethyl-6-methylidene-2-tricyclo[6.2.1.01,5]undecanyl]methanol |
| Q27289660 |
| AKOS040746956 |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID337606 | Displacement of [3H]AVP from vasopressin V1a receptor in rat liver membrane at 25 uM by competitive displacement assay | 1994 | Journal of natural products, Oct, Volume: 57, Issue:10 | Khusimol, a non-peptide ligand for vasopressin V1a receptors. |
| AID337608 | Displacement of [3H]AVP from vasopressin V1a receptor in rat liver membrane | 1994 | Journal of natural products, Oct, Volume: 57, Issue:10 | Khusimol, a non-peptide ligand for vasopressin V1a receptors. |
| AID337609 | Displacement of [3H]AVP from vasopressin V1a receptor in rat liver membrane by competitive displacement assay | 1994 | Journal of natural products, Oct, Volume: 57, Issue:10 | Khusimol, a non-peptide ligand for vasopressin V1a receptors. |
| AID337607 | Displacement of [3H]AVP from vasopressin V1a receptor in rat liver membrane at 50 uM by competitive displacement assay | 1994 | Journal of natural products, Oct, Volume: 57, Issue:10 | Khusimol, a non-peptide ligand for vasopressin V1a receptors. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (29.56) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 6 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||