Compounds > gelsemoxonine
Page last updated: 2024-11-13

gelsemoxonine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

gelsemoxonine: isolated from Gelsemium elegans Benth; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

FloraRankFlora DefinitionFamilyFamily Definition
GelsemiumgenusA plant genus of the family LOGANIACEAE (classified by some botanists as Gelsemiaceae). The sometimes used common name of trumpet flower is also used for DATURA.[MeSH]Gelsemiaceae[no description available]
Gelsemium elegansspecies[no description available]Gelsemiaceae[no description available]

Cross-References

ID SourceID
PubMed CID44583831
CHEMBL ID524079
MeSH IDM0455350

Synonyms (2)

Synonym
gelsemoxonine
CHEMBL524079

Research Excerpts

Overview

Gelsemoxonine (1) is a Gelsemium alkaloid incorporating an unusual azetidine.

ExcerptReferenceRelevance
"Gelsemoxonine (1) is a Gelsemium alkaloid incorporating an unusual azetidine. "( Total synthesis of (±)-Gelsemoxonine.
Carreira, EM; Diethelm, S, 2013)		2.14
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID376637Cytotoxicity against human A431 cells after 48 hrs by trypan blue test2006Journal of natural products, Apr, Volume: 69, Issue:4
Isolation of gelsedine-type indole alkaloids from Gelsemium elegans and evaluation of the cytotoxic activity of gelsemium alkaloids for A431 epidermoid carcinoma cells.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's3 (50.00)24.3611
2020's1 (16.67)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 20.41

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index20.41 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.72 (4.65)
Search Engine Demand Index15.26 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (20.41)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
octane
Octanes: Eight-carbon saturated hydrocarbon group of the methane series. Include isomers and derivatives.. octane : A straight chain alkane composed of 8 carbon atoms.		2.3110alkanexenobiotic
isoxazoles
Isoxazoles: Azoles with an OXYGEN and a NITROGEN next to each other at the 1,2 positions, in contrast to OXAZOLES that have nitrogens at the 1,3 positions.. isoxazole : A monocyclic heteroarene with a structure consisting of a 5-membered ring containing three carbon atoms and an oxygen and nitrogen atom adjacent to each other. It is the parent of the class of isoxazoles.. isoxazoles : Oxazoles in which the N and O atoms are adjacent.		2.1110isoxazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
azetidine
[no description available]		7.0110azacycloalkane;
azetidines;
saturated organic heteromonocyclic parent
alkenes
[no description available]		2.3110
humantenine
humantenine: isolated from root of Hu-Man-Teng (Gelsemium elegans Benth.); structure given in first source		2.0310
ConditionIndicatedRelationship StrengthStudiesTrials