flustramine A: from Flustra foliacea L.; exhibits muscle relaxant activity both in vivo & in vitro; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 636869 |
| CHEMBL ID | 538411 |
| MeSH ID | M0122423 |
| Synonym |
|---|
| rel-(3ar,8ar)-6-bromo-3a-(1,1-dimethylprop-2-en-1-yl)-1-methyl-8-(3-methylbut-2-en-1-yl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole |
| inchi=1/c21h29brn2/c1-7-20(4,5)21-11-13-23(6)19(21)24(12-10-15(2)3)18-14-16(22)8-9-17(18)21/h7-10,14,19h,1,11-13h2,2-6h3/t19-,21-/m1/s |
| pyrrolo[2,3-b]indole, 6-bromo-3a-(1,1-dimethyl-2-propenyl)-1,2,3,3a,8,8a-hexahydro-1-methyl-8-(3-methyl-2-butenyl)-, (3ar,8ar)- |
| 6-bromo-3a-(1,1-dimethyl-allyl)-1-methyl-8-(3-methyl-but-2-enyl)-1,2,3,3a,8,8a-hexahydro-pyrrolo[2,3-b]indole |
| 71239-64-0 |
| flustramine a |
| 6-bromo-1-methyl-3a-(1,1-dimethyl-allyl)-8-(3-methyl-but-2-enyl)-1,2,3,3a,8,8a-hexahydro-pyrrolo[2,3-b]indole |
| CHEMBL538411 |
| (3ar,8br)-6-bromo-3-methyl-8b-(2-methylbut-3-en-2-yl)-4-(3-methylbut-2-enyl)-2,3a-dihydro-1h-pyrrolo[2,3-b]indole |
| DTXSID80991548 |
| 6-bromo-1-methyl-3a-(2-methylbut-3-en-2-yl)-8-(3-methylbut-2-en-1-yl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID397819 | Blockade of voltage-activated rat Kv1.4 potassium channel expressed in Xenopus laevis oocytes assessed as effect on evoked current upto 10 uM by two-electrode voltage clamp method | 2002 | Journal of natural products, Nov, Volume: 65, Issue:11 | Four new bromotryptamine derivatives from the marine bryozoan Flustra foliacea. |
| AID397820 | Blockade of voltage-activated rat brain Nav1.2 sodium channel type 2 channel expressed in Xenopus laevis oocytes assessed as effect on evoked current by two-electrode voltage clamp method | 2002 | Journal of natural products, Nov, Volume: 65, Issue:11 | Four new bromotryptamine derivatives from the marine bryozoan Flustra foliacea. |
| AID397818 | Blockade of voltage-activated rat Kv1.1 potassium channel expressed in Xenopus laevis oocytes assessed as effect on evoked current upto 10 uM by two-electrode voltage clamp method | 2002 | Journal of natural products, Nov, Volume: 65, Issue:11 | Four new bromotryptamine derivatives from the marine bryozoan Flustra foliacea. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 6 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||