cytoskyrin a

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

cytoskyrin A: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	44566948
CHEMBL ID	449103
MeSH ID	M0377971

Synonyms (2)

Synonym
CHEMBL449103
cytoskyrin a

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (10)

Assay ID	Title	Year	Journal	Article
AID334567	Antibacterial activity against Escherichia coli ATCC 25922 at 10 ug/disk by agar plate diffusion assay	2002	Journal of natural products, May, Volume: 65, Issue:5	New metabolites from sponge-derived fungi Curvularia lunata and Cladosporium herbarum.
AID334575	Antifungal activity against Candida albicans at 10 ug/disk by agar plate diffusion assay	2002	Journal of natural products, May, Volume: 65, Issue:5	New metabolites from sponge-derived fungi Curvularia lunata and Cladosporium herbarum.
AID334568	Antibacterial activity against Escherichia coli HBI 101 at 5 ug/disk by agar plate diffusion assay	2002	Journal of natural products, May, Volume: 65, Issue:5	New metabolites from sponge-derived fungi Curvularia lunata and Cladosporium herbarum.
AID334574	Antifungal activity against Candida albicans at 5 ug/disk by agar plate diffusion assay	2002	Journal of natural products, May, Volume: 65, Issue:5	New metabolites from sponge-derived fungi Curvularia lunata and Cladosporium herbarum.
AID334566	Antibacterial activity against Bacillus subtilis 168 at 10 ug/disk by agar plate diffusion assay	2002	Journal of natural products, May, Volume: 65, Issue:5	New metabolites from sponge-derived fungi Curvularia lunata and Cladosporium herbarum.
AID334564	Antibacterial activity against Bacillus subtilis 168 at 5 ug/disk by agar plate diffusion assay	2002	Journal of natural products, May, Volume: 65, Issue:5	New metabolites from sponge-derived fungi Curvularia lunata and Cladosporium herbarum.
AID334563	Antibacterial activity against Staphylococcus aureus ATCC 25923 at 10 ug/disk by agar plate diffusion assay	2002	Journal of natural products, May, Volume: 65, Issue:5	New metabolites from sponge-derived fungi Curvularia lunata and Cladosporium herbarum.
AID334562	Antibacterial activity against Staphylococcus aureus ATCC 25923 at 5 ug/disk by agar plate diffusion assay	2002	Journal of natural products, May, Volume: 65, Issue:5	New metabolites from sponge-derived fungi Curvularia lunata and Cladosporium herbarum.
AID334565	Antibacterial activity against Escherichia coli ATCC 25922 at 5 ug/disk by agar plate diffusion assay	2002	Journal of natural products, May, Volume: 65, Issue:5	New metabolites from sponge-derived fungi Curvularia lunata and Cladosporium herbarum.
AID334569	Antibacterial activity against Escherichia coli HBI 101 at 10 ug/disk by agar plate diffusion assay	2002	Journal of natural products, May, Volume: 65, Issue:5	New metabolites from sponge-derived fungi Curvularia lunata and Cladosporium herbarum.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	5 (71.43)	29.6817
2010's	2 (28.57)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.75

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	12.75 (24.57)
Research Supply Index	2.08 (2.92)
Research Growth Index	4.83 (4.65)
Search Engine Demand Index	0.00 (26.88)
Search Engine Supply Index	0.00 (0.95)

This Compound (12.75)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	7 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
pyridine azine : An organonitrogen compound of general structure RCH=N-N=CHR or RR'C=N-N=CRR'.	2.17	1	azaarene; mancude organic heteromonocyclic parent; monocyclic heteroarene; pyridines	environmental contaminant; NMR chemical shift reference compound
emodin Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.. emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.	2.15	1	trihydroxyanthraquinone	antineoplastic agent; laxative; plant metabolite; tyrosine kinase inhibitor
chrysophanic acid chrysophanic acid: RN given refers to parent cpd; structure in Merck, 9th ed, #2260. chrysophanol : A trihydroxyanthraquinone that is chrysazin with a methyl substituent at C-3. It has been isolated from Aloe vera and exhibits antiviral and anti-inflammatory activity.	2.15	1	dihydroxyanthraquinone	anti-inflammatory agent; antiviral agent; plant metabolite
skyrin skyrin: main pigment of toxin rice fungus Penicillium islandicum; RN given refers to parent cpd; structure	7.02	1	biaryl; trihydroxyanthraquinone
naphthoquinones Naphthoquinones: Naphthalene rings which contain two ketone moieties in any position. They can be substituted in any position except at the ketone groups.	2.43	2
abscisic acid Abscisic Acid: Abscission-accelerating plant growth substance isolated from young cotton fruit, leaves of sycamore, birch, and other plants, and from potatoes, lemons, avocados, and other fruits.. (S)-2-trans-abscisic acid : A 2-trans-abscisic acid with (S)-configuration at the chiral centre.. (+)-abscisic acid : The naturally occurring (1'S)-(+) enantiomer of abscisic acid. It is an important sesquiterpenoid plant hormone which acts as a regulator of plant responses to environmental stresses such as drought and cold.	2.01	1	2-trans-abscisic acid
rugulosin rugulosin: RN given refers to cpd without isomeric designation; structure in first source & in Negwer, 5th ed, #5799	2.75	3
flavoskyrin flavoskyrin: isolated from Penicillium islandicum Sopp.; structure given in first source	7.47	2

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