Page last updated: 2024-11-12
botcinic acid
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
botcinic acid: from the grey mould fungus Botrytis cinerea; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 11509607 |
| CHEMBL ID | 496242 |
| MeSH ID | M0568983 |
Synonyms (6)
| Synonym |
|---|
| botcinic acid |
| inchi=1/c20h34o8/c1-6-7-8-14(21)9-10-15(22)27-16-11(2)17(23)20(5,28-13(16)4)18(24)12(3)19(25)26/h9-14,16-18,21,23-24h,6-8h2,1-5h3,(h,25,26)/b10-9+/t11?,12?,13?,14?,16?,17?,18?,20-/m0/s |
| CHEMBL496242 |
| (2r,3s)-3-hydroxy-3-[(2s,3s,4s,5r,6s)-3-hydroxy-5-[(e,4s)-4-hydroxyoct-2-enoyl]oxy-2,4,6-trimethyloxan-2-yl]-2-methylpropanoic acid |
| 958734-32-2 |
| DTXSID401043714 |
Research Excerpts
Overview
Botcinic acid is a phytotoxic polyketide involved in the virulence of the gray mold fungus Botrytis cinerea.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Botcinic acid is a phytotoxic polyketide involved in the virulence of the gray mold fungus Botrytis cinerea. " | ( Botcinic acid biosynthesis in Botrytis cinerea relies on a subtelomeric gene cluster surrounded by relics of transposons and is regulated by the Zn Collado, IG; Dalmais, B; Moraga, J; Morgant, G; Porquier, A; Sghyer, H; Simon, A; Viaud, M, 2019) | 3.4 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (1)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID376641 | Antifungal activity against Magnaporthe grisea | 2006 | Journal of natural products, Apr, Volume: 69, Issue:4 | Botcinins E and F and Botcinolide from Botrytis cinerea and structural revision of botcinolides. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (5)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 13.28
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (13.28) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||