aureonitol: structure in first source [MeSH]
| ID Source | ID |
|---|---|
| PubMed CID | 25064137 |
| CHEMBL ID | 4852954 |
| MeSH ID | M0526997 |
| Synonym |
|---|
| 23F04FI61S , |
| 3-furanol, 2-(1,3-butadien-1-yl)tetrahydro-4-(1,3-pentadien-1-yl)-, (2s,3r,4s)- |
| (-)-aureonitol |
| aureonitol |
| AKOS030213172 |
| 71774-51-1 |
| unii-23f04fi61s |
| NCGC00381388-01 |
| Q27253745 |
| (2s,3r,4s)-2-[(1e)-buta-1,3-dienyl]-4-[(1e,3e)-penta-1,3-dienyl]oxolan-3-ol |
| (2s,3r,4s)-2-[(1e)-buta-1,3-dien-1-yl]-4-[(1e,3e)-penta-1,3-dien-1-yl]oxolan-3-ol |
| CHEMBL4852954 |
| DTXSID601038840 |
| (2s,3r,4s)-2-((e)-buta-1,3-dien-1-yl)-4-((1e,3e)-penta-1,3-dien-1-yl)tetrahydrofuran-3-ol |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1 ISSN: 2472-5560 | Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1347160 | Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49 ISSN: 1091-6490 | Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347159 | Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49 ISSN: 1091-6490 | Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5 ISSN: 1521-0111 | A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5 ISSN: 1521-0111 | A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1782547 | Cytotoxicity against mouse BV-2 cells assessed as reduction in cell viability at 120 uM after 24 hrs by MTT assay | 2021 | Journal of natural products, 12-24, Volume: 84, Issue:12 ISSN: 1520-6025 | Aureonitol Analogues and Orsellinic Acid Esters Isolated from |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 3 (33.33) | 2.80 |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 9 (100.00%) | 84.16% |
| Substance | Studies | Classes | Roles | First Year | Last Year | Average Age | Relationship Strength | Trials | pre-1990 | 1990's | 2000's | 2010's | post-2020 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| tetrahydrofuran | cyclic ether; oxolanes; saturated organic heteromonocyclic parent; volatile organic compound | polar aprotic solvent | 2015 | 2015 | 9.0 | high | 0 | 0 | 0 | 0 | 1 | 0 | |
| orsellinic acid | dihydroxybenzoic acid; resorcinols | fungal metabolite; marine metabolite; metabolite | 2021 | 2021 | 3.0 | high | 0 | 0 | 0 | 0 | 0 | 1 | |
| chaetoglobosins | 2018 | 2018 | 6.0 | high | 0 | 0 | 0 | 0 | 1 | 0 |
| Condition | Indicated | Studies | First Year | Last Year | Average Age | Relationship Strength | Trials | pre-1990 | 1990's | 2000's | 2010's | post-2020 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Congenital Zika Syndrome | 0 | 2020 | 2020 | 4.0 | high | 0 | 0 | 0 | 0 | 1 | 0 | |
| Disease Models, Animal | 0 | 2020 | 2020 | 4.0 | high | 0 | 0 | 0 | 0 | 1 | 0 | |
| Zika Virus Infection | 0 | 2020 | 2020 | 4.0 | high | 0 | 0 | 0 | 0 | 1 | 0 |
| Article | Year |
|---|---|
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology, , Volume: 96, Issue:5 | 2019 |