Page last updated: 2024-11-06

2-diazofluorene

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

2-diazofluorene is a diazo compound with the molecular formula C13H8N2. It is a yellow solid that is sensitive to light and heat. 2-diazofluorene is a versatile synthetic reagent used in organic chemistry, particularly in the synthesis of complex molecules. It is a valuable precursor to various heterocyclic compounds, including pyrazoles and triazoles, through reactions such as cycloaddition and electrophilic aromatic substitution. Its importance in organic synthesis stems from its ability to act as a carbene precursor, generating highly reactive intermediates that can participate in a range of organic transformations. 2-diazofluorene is also studied for its potential applications in materials science, particularly in the development of organic light-emitting diodes (OLEDs) and photovoltaics. Research efforts focus on understanding its photophysical properties and exploring its suitability as a building block for functional materials. 2-diazofluorene is a highly reactive compound, and its handling requires caution due to its potential for explosion. Proper safety measures should be taken when working with this compound.'

2-diazofluorene: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID70028
CHEMBL ID386841
SCHEMBL ID482108
MeSH IDM0149689

Synonyms (19)

Synonym
nsc167093
9h-fluorene, 9-diazo-
9-diazofluorene
nsc-167093
fluorene, 9-diazo-
832-80-4
2-diazofluorene
CHEMBL386841
9-diazo-fluorene
fluorene, 9-diazo- (van)
8be76eab5e ,
unii-8be76eab5e
nsc 167093
FT-0621644
AKOS015900580
DTXSID50232218
SCHEMBL482108
9-diazo-9h-fluorene
diazofluorene
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (2)

Assay IDTitleYearJournalArticle
AID270444Conversion of type 1 supercoiled DNA to type 2 nicked DNA2006Bioorganic & medicinal chemistry letters, Oct-01, Volume: 16, Issue:19
Mimicking the biological activity of diazobenzo[b]fluorene natural products with electronically tuned diazofluorene analogs.
AID270443Conversion of type 1 supercoiled DNA to type 2 nicked DNA in presence of dithiothreitol2006Bioorganic & medicinal chemistry letters, Oct-01, Volume: 16, Issue:19
Mimicking the biological activity of diazobenzo[b]fluorene natural products with electronically tuned diazofluorene analogs.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (11)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (9.09)18.7374
1990's6 (54.55)18.2507
2000's4 (36.36)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (9.09%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other10 (90.91%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]