Azidopyrene is a versatile building block for the synthesis of various pyrene-containing molecules. It is typically synthesized through the reaction of pyrene with an azide reagent, such as sodium azide. The azide group in azidopyrene is highly reactive and can undergo various transformations, such as cycloaddition reactions, to form new compounds. Azidopyrene has potential applications in fields such as materials science, bioimaging, and drug discovery. For example, it can be used to create fluorescent probes for bioimaging and to synthesize new materials with interesting optical properties. The unique properties of azidopyrene, including its fluorescence, reactivity, and ability to form stable conjugates, make it an attractive compound for further research and development.'
azidopyrene: hydrophobic, photolabile probe [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 115167 |
| SCHEMBL ID | 19100108 |
| MeSH ID | M0091848 |
| Synonym |
|---|
| azidopyrene |
| 1-azidopyrene |
| 36171-39-8 |
| pyrene, 1-azido- |
| DTXSID90189737 |
| SCHEMBL19100108 |
| ap [1-azidopyrene] |
| LCZC3796 |
1-Azidopyrene was found to be a competitive inhibitor of [3H]B[a]P binding.
| Excerpt | Reference | Relevance |
|---|---|---|
| "1-Azidopyrene was found to be a competitive inhibitor of [3H]B[a]P binding." | ( Purification of a benzo[a]pyrene binding protein by affinity chromatography and photoaffinity labeling. Collins, S; Marletta, MA, 1986) | 0.83 |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.06) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 7 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||