Page last updated: 2024-12-06
1,5-naphthylene di-isocyanate
Description
## 1,5-Naphthylene Di-isocyanate (NDI)
1,5-Naphthylene di-isocyanate (NDI) is an organic compound with the chemical formula C12H6N2O2. It is a **diisocyanate**, meaning it contains two isocyanate (-N=C=O) groups. These groups are attached to a naphthalene ring, which is a fused aromatic ring system consisting of two benzene rings.
**Importance in Research:**
NDI is an important compound in research for several reasons:
* **Monomer for High-Performance Polymers:** NDI is a key monomer used in the synthesis of various high-performance polymers, including polyimides, polyamides, and polyurethanes. These polymers exhibit excellent properties like high thermal stability, mechanical strength, and chemical resistance, making them suitable for applications in aerospace, electronics, and automotive industries.
* **Organic Electronics:** NDI-based polymers are employed in organic electronics due to their ability to transport charge carriers efficiently. They find use in transistors, solar cells, and organic light-emitting diodes (OLEDs).
* **Advanced Materials:** NDI can be incorporated into various materials to enhance their properties. For example, it can be used to create self-healing materials, stimuli-responsive materials, and materials with improved mechanical properties.
* **Catalysis:** NDI derivatives have been explored as catalysts for various organic reactions, particularly in the field of green chemistry.
* **Biomedical Applications:** NDI has been investigated for its potential use in biomaterials, drug delivery systems, and tissue engineering.
**Key Advantages of NDI:**
* **High Reactivity:** The isocyanate groups in NDI are highly reactive, enabling efficient polymerization and modification reactions.
* **Planar Structure:** The rigid planar structure of NDI promotes strong intermolecular interactions, contributing to the excellent mechanical and thermal properties of resulting polymers.
* **Electron-Deficient Nature:** NDI's electron-deficient nature makes it a good acceptor in charge-transfer complexes, which is crucial for its applications in organic electronics.
**Overall, 1,5-Naphthylene di-isocyanate is a versatile building block with vast potential for creating innovative materials with advanced properties.** Research efforts continue to explore its diverse applications in various fields, including materials science, chemistry, and engineering.
1,5-naphthylene di-isocyanate: implicated in occupational asthma [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
ID Source | ID |
PubMed CID | 18503 |
CHEBI ID | 82496 |
SCHEMBL ID | 22210 |
MeSH ID | M0080713 |
Synonyms (41)
Synonym |
naphthalene, 1,5-diisocyanato- |
1,5-naphthylene di-isocyanate |
3173-72-6 |
isocyanic acid,5-naphthylene ester |
1,5-naphthylene diisocyanate |
nsc-240728 |
1,5-naphthalene diisocyanate , |
nsc240728 |
1,5-diisocyanatonaphthalene |
naphthalene,5-diisocyanato- |
nsc 240728 |
1,5-naphthyl diisocyanate |
isocyanic acid, 1,5-naphthylene ester |
brn 2212353 |
einecs 221-641-4 |
1,5-naphthalene diisocyanate [diisocyanates] |
ccris 8920 |
N0168 |
naphthalene 1,5-diisocyanate |
C19464 |
unii-0orb22st7m |
4-13-00-00342 (beilstein handbook reference) |
0orb22st7m , |
ec 221-641-4 |
1,5-diisocyanatonaphthalene;1,5-naphthylene diisocyanate |
A820975 |
FT-0600668 |
AKOS015900717 |
SCHEMBL22210 |
CHEBI:82496 |
mfcd00039588 |
SBJCUZQNHOLYMD-UHFFFAOYSA-N |
1,5-naphthalenediol, diisocyanate |
1,5-naphthalene diisocyanate [iarc] |
1,5-ndi |
naphthalene diisocyanate, 1,5- |
DTXSID8040145 |
GS-3153 |
1,5-naphthalenediisocyanate |
Q2786152 |
D91652 |
Drug Classes (1)
Class | Description |
naphthalenes | Any benzenoid aromatic compound having a skeleton composed of two ortho-fused benzene rings. |
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Research
Studies (7)
Timeframe | Studies, This Drug (%) | All Drugs % |
pre-1990 | 1 (14.29) | 18.7374 |
1990's | 1 (14.29) | 18.2507 |
2000's | 3 (42.86) | 29.6817 |
2010's | 2 (28.57) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.27
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
Metric | This Compound (vs All) |
---|
Research Demand Index | 12.27 (24.57) | Research Supply Index | 2.40 (2.92) | Research Growth Index | 4.66 (4.65) | Search Engine Demand Index | 0.00 (26.88) | Search Engine Supply Index | 0.00 (0.95) |
| |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 4 (40.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 6 (60.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |