Page last updated: 2024-11-05

1,2-diethylbenzene

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID8657
CHEMBL ID3186870
MeSH IDM0178262

Synonyms (56)

Synonym
BIDD:ER0356
135-01-3
LS-13808
hsdb 4081
un2049
nsc 405068
diethylbenzol
o-diethylbenzene
brn 1904392
einecs 205-170-1
brn 1903396
einecs 246-874-9
ai3-15336
benzene, o-diethyl-
benzene, diethyl-
inchi=1/c10h14/c1-3-9-7-5-6-8-10(9)4-2/h5-8h,3-4h2,1-2h
benzene, 1,2-diethyl-
1,2-diethylbenzene
1,2-diethylbenzene, technical grade, 92%
1,2-diethylbenzene, >=99.0% (gc)
A806866
cas-25340-17-4
dsstox_rid_78595
NCGC00257453-01
dsstox_gsid_27866
dsstox_cid_7866
tox21_303467
tox21_202258
NCGC00259807-01
1,2-diethyl-benzene
ec 246-874-9
9a18z78q73 ,
4-05-00-01067 (beilstein handbook reference)
unii-9a18z78q73
diethylbenzene [un2049] [flammable liquid]
4-05-00-01065 (beilstein handbook reference)
25hox6t1lu ,
unii-25hox6t1lu
FT-0606393
FT-0624880
AKOS015888421
1,2-diethylbenzene [hsdb]
J-503819
DTXSID6052742
diethyl benzene
3,4-diethylbenzene
1,2-diethyl benzene
1,2-diethyibenzene
ortho-diethylbenzene
CHEMBL3186870
mfcd00009258
mfcd00792900
1,2-diethylbenzene 100 microg/ml in methanol
benzene, 1,2-diethyl-; benzene, o-diethyl- (8ci); 1,2-diethylbenzene; o-diethylbenzene
Q2429316
EN300-112423

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" In conclusion, this study demonstrated that 1,2-DEB causes mild foetotoxicity at maternal toxic doses and that the exposure of the developing rat foetus to 1,2-DEB and/or metabolites after maternal administration of 1,2-DEB in late gestation is small."( Assessment of the developmental toxicity and placental transfer of 1,2-diethylbenzene in rats.
Beydon, D; Fabry, JP; Gallissot, F; Langonné, I; Payan, JP; Sabaté, JP; Saillenfait, AM, 1999
)
0.54
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (4)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
estrogen receptor 2 (ER beta)Homo sapiens (human)Potency9.93660.000657.913322,387.1992AID1259377
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency52.88540.003041.611522,387.1992AID1159552; AID1159555
farnesoid X nuclear receptorHomo sapiens (human)Potency7.09210.375827.485161.6524AID743220
peroxisome proliferator-activated receptor deltaHomo sapiens (human)Potency63.32290.001024.504861.6448AID743215
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (12)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's5 (41.67)18.2507
2000's6 (50.00)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 32.79

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index32.79 (24.57)
Research Supply Index2.56 (2.92)
Research Growth Index4.31 (4.65)
Search Engine Demand Index42.09 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (32.79)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other12 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]