Page last updated: 2024-12-07

1,2,3,4,6-penta-o-acetylgalactopyranose

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

## 1,2,3,4,6-Penta-O-acetyl-D-galactopyranose: A Sweet Research Tool

1,2,3,4,6-Penta-O-acetyl-D-galactopyranose, also known as **penta-acetylated galactose**, is a derivative of the sugar galactose. It is a white, crystalline solid that is soluble in organic solvents.

**Structure:**

The molecule is named based on its structure:

* **D-galactopyranose:** Indicates the underlying sugar structure is galactose in its pyranose form (a six-membered ring).
* **Penta-O-acetyl:** Indicates the presence of five acetyl groups (CH3CO-) attached to the oxygen atoms (O) of the sugar molecule.

**Importance in Research:**

Penta-acetylated galactose plays a crucial role in various research fields, including:

* **Glycosylation Chemistry:** This compound is often used as a building block in the synthesis of complex carbohydrates, glycoconjugates (molecules with sugar moieties attached), and other biologically important molecules. This is due to its **reactivity** - the acetyl groups protect the hydroxyl groups on the galactose ring, allowing specific reactions to occur at desired sites.
* **Glycobiology Studies:** It serves as a model compound for investigating the properties and functions of galactose-containing molecules. It can be used to study:
* **Enzymatic activity:** Analyzing how enzymes interact with and modify galactose residues.
* **Biological recognition:** Investigating how cells and organisms recognize and interact with galactose-containing molecules.
* **Materials Science:** Penta-acetylated galactose can be used as a component in the synthesis of polymers and other materials with tunable properties. This is due to its ability to form self-assembled structures and its compatibility with other monomers.
* **Drug Discovery:** It is used as a starting material for synthesizing potential drug candidates that target carbohydrate-binding proteins involved in various diseases.

**Benefits of using Penta-acetylated Galactose:**

* **Stability:** It is more stable than unprotected galactose, making it easier to handle and store.
* **Solubility:** Its solubility in organic solvents simplifies its use in various chemical reactions.
* **Reactivity:** The acetyl groups can be selectively removed, enabling the controlled modification of the galactose molecule.

Overall, 1,2,3,4,6-Penta-O-acetyl-D-galactopyranose is a valuable tool for researchers across various disciplines. Its unique properties and versatility make it a cornerstone in advancing our understanding of carbohydrate chemistry and its implications in various biological and technological fields.

Cross-References

ID SourceID
PubMed CID94752
SCHEMBL ID133205
MeSH IDM0074187

Synonyms (44)

Synonym
4163-60-4
.beta.-d-galactopyranose, pentaacetate
beta-d-galactose pentaacetate, 98%
beta-d-galactose pentaacetate ,
G0247
penta-o-acetyl-beta-d-galactopyranose
b-d-galactose pentaacetate
[(2r,3s,4s,5r,6s)-3,4,5,6-tetraacetyloxyoxan-2-yl]methyl acetate
AKOS015924810
nsc 1353
nsc 170188
1,2,3,4,6-penta-o-acetylgalactopyranose
1,2,3,4,6-penta-o-acetyl-beta-d-galactopyranose
beta-penta-o-acetyl-d-galactopyranose
einecs 224-008-0
beta-d-galactopyranose, 1,2,3,4,6-pentaacetate
beta-d-galactopyranose pentaacetate
nsc 119334
beta-d-galactopyranose, pentaacetate
beta-d-galactose pentaacetate (van)
ai3-19585
beta-d-galactosepentaacetate
(2s,3r,4s,5s,6r)-6-(acetoxymethyl)tetrahydro-2h-pyran-2,3,4,5-tetrayl tetraacetate
G-1781
SCHEMBL133205
pentaacetyl-.beta.-d-galactose
galactopyranose, pentaacetate, .beta.-d-
1,2,3,4,6-penta-o-acetyl-.beta.-d-galactopyranose
.beta.-pentaacetylgalactose
galactopyranose, pentaacetate, beta-d-
penta-o-acetyl-.beta.-d-galactopyranose
1,2,3,4,6-penta-o-acetyl-.beta.-d-galactose
AC-24182
F20333
2,3,4,6-tetraacetyl-i(2)-acetyl-d-galaktose
Q63409498
AMY24720
FS-3978
.beta.-d-galactopyranose, 1,2,3,4,6-pentaacetate
DTXSID20883736
-d-galactose pentaacetate
d-galactosepenta-acetate
(2s,3r,4s,5s,6r)-6-(acetoxymethyl)tetrahydro-2h-pyran-2,3,4,5-tetrayltetraacetate
beta -d-galactose pentaacetate
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (20.00)18.7374
1990's0 (0.00)18.2507
2000's4 (80.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.90

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.90 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.69 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.90)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]