## 1,2,3,4,6-Penta-O-acetyl-D-galactopyranose: A Sweet Research Tool
1,2,3,4,6-Penta-O-acetyl-D-galactopyranose, also known as **penta-acetylated galactose**, is a derivative of the sugar galactose. It is a white, crystalline solid that is soluble in organic solvents.
**Structure:**
The molecule is named based on its structure:
* **D-galactopyranose:** Indicates the underlying sugar structure is galactose in its pyranose form (a six-membered ring).
* **Penta-O-acetyl:** Indicates the presence of five acetyl groups (CH3CO-) attached to the oxygen atoms (O) of the sugar molecule.
**Importance in Research:**
Penta-acetylated galactose plays a crucial role in various research fields, including:
* **Glycosylation Chemistry:** This compound is often used as a building block in the synthesis of complex carbohydrates, glycoconjugates (molecules with sugar moieties attached), and other biologically important molecules. This is due to its **reactivity** - the acetyl groups protect the hydroxyl groups on the galactose ring, allowing specific reactions to occur at desired sites.
* **Glycobiology Studies:** It serves as a model compound for investigating the properties and functions of galactose-containing molecules. It can be used to study:
* **Enzymatic activity:** Analyzing how enzymes interact with and modify galactose residues.
* **Biological recognition:** Investigating how cells and organisms recognize and interact with galactose-containing molecules.
* **Materials Science:** Penta-acetylated galactose can be used as a component in the synthesis of polymers and other materials with tunable properties. This is due to its ability to form self-assembled structures and its compatibility with other monomers.
* **Drug Discovery:** It is used as a starting material for synthesizing potential drug candidates that target carbohydrate-binding proteins involved in various diseases.
**Benefits of using Penta-acetylated Galactose:**
* **Stability:** It is more stable than unprotected galactose, making it easier to handle and store.
* **Solubility:** Its solubility in organic solvents simplifies its use in various chemical reactions.
* **Reactivity:** The acetyl groups can be selectively removed, enabling the controlled modification of the galactose molecule.
Overall, 1,2,3,4,6-Penta-O-acetyl-D-galactopyranose is a valuable tool for researchers across various disciplines. Its unique properties and versatility make it a cornerstone in advancing our understanding of carbohydrate chemistry and its implications in various biological and technological fields.
ID Source | ID |
---|---|
PubMed CID | 94752 |
SCHEMBL ID | 133205 |
MeSH ID | M0074187 |
Synonym |
---|
4163-60-4 |
.beta.-d-galactopyranose, pentaacetate |
beta-d-galactose pentaacetate, 98% |
beta-d-galactose pentaacetate , |
G0247 |
penta-o-acetyl-beta-d-galactopyranose |
b-d-galactose pentaacetate |
[(2r,3s,4s,5r,6s)-3,4,5,6-tetraacetyloxyoxan-2-yl]methyl acetate |
AKOS015924810 |
nsc 1353 |
nsc 170188 |
1,2,3,4,6-penta-o-acetylgalactopyranose |
1,2,3,4,6-penta-o-acetyl-beta-d-galactopyranose |
beta-penta-o-acetyl-d-galactopyranose |
einecs 224-008-0 |
beta-d-galactopyranose, 1,2,3,4,6-pentaacetate |
beta-d-galactopyranose pentaacetate |
nsc 119334 |
beta-d-galactopyranose, pentaacetate |
beta-d-galactose pentaacetate (van) |
ai3-19585 |
beta-d-galactosepentaacetate |
(2s,3r,4s,5s,6r)-6-(acetoxymethyl)tetrahydro-2h-pyran-2,3,4,5-tetrayl tetraacetate |
G-1781 |
SCHEMBL133205 |
pentaacetyl-.beta.-d-galactose |
galactopyranose, pentaacetate, .beta.-d- |
1,2,3,4,6-penta-o-acetyl-.beta.-d-galactopyranose |
.beta.-pentaacetylgalactose |
galactopyranose, pentaacetate, beta-d- |
penta-o-acetyl-.beta.-d-galactopyranose |
1,2,3,4,6-penta-o-acetyl-.beta.-d-galactose |
AC-24182 |
F20333 |
2,3,4,6-tetraacetyl-i(2)-acetyl-d-galaktose |
Q63409498 |
AMY24720 |
FS-3978 |
.beta.-d-galactopyranose, 1,2,3,4,6-pentaacetate |
DTXSID20883736 |
-d-galactose pentaacetate |
d-galactosepenta-acetate |
(2s,3r,4s,5s,6r)-6-(acetoxymethyl)tetrahydro-2h-pyran-2,3,4,5-tetrayltetraacetate |
beta -d-galactose pentaacetate |
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 1 (20.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 4 (80.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.90) All Compounds (24.57) |
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 5 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |