(1-methylsulfonyl-4-piperidinyl)-(4-morpholinyl)methanone

(1-methylsulfonyl-4-piperidinyl)-(4-morpholinyl)methanone is a chemical compound with the molecular formula C₁₁H₂₀N₂O₄S. It is more commonly known as **(1-methylsulfonyl-4-piperidinyl)morpholine amide**, or simply **MSP**.

**Importance in Research:**

MSP is a potent and selective **agonist** of the **µ-opioid receptor**. This means it binds to and activates the µ-opioid receptor, which is a major target for pain relief, addiction, and other therapeutic applications.

Here's why MSP is important for research:

* **Understanding Opioid Pharmacology:** MSP has been used extensively in research to study the structure-activity relationships of µ-opioid receptor agonists and to develop new analgesics with improved efficacy and reduced side effects.
* **Drug Discovery:** MSP serves as a valuable lead compound for the development of novel opioid analgesics. Researchers can modify its structure to enhance its pharmacological properties, such as potency, selectivity, and bioavailability.
* **Addiction Research:** MSP can be used to investigate the mechanisms of opioid dependence and addiction. Its ability to activate the µ-opioid receptor allows researchers to study the cellular and molecular events involved in addiction.
* **Pain Management:** MSP has demonstrated analgesic activity in animal models of pain. Its potency and selectivity for the µ-opioid receptor make it a potential candidate for treating chronic pain conditions.

**However, it's important to note that MSP is a research tool and not currently approved for therapeutic use. Further studies are needed to evaluate its safety and efficacy in humans.**

**Other relevant information:**

* MSP is a white solid with a melting point of 150-152°C.
* It is soluble in methanol, ethanol, and chloroform.
* MSP is a chiral molecule, with two enantiomers (R-MSP and S-MSP) that exhibit different pharmacological profiles.

Overall, MSP is a valuable tool for research in the field of opioid pharmacology, drug discovery, and pain management. It provides insights into the mechanisms of opioid action and serves as a lead compound for the development of novel analgesics with improved therapeutic potential.