Page last updated: 2024-11-08
phaseollin (isoflavan)
Description
phaseollin (isoflavan): an isoflavonoid phytoalexin synthesized in response to injury, from snap or French bean, Phaseolus vulgaris & soybean; delays growth of Candida albicans; structure in first source; do not confuse with phaseolin (single L), a plant storage protein also produced by Phaseolus vulgaris; [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
(-)-phaseollinisoflavan : A member of the class of hydroxyisoflavans that is (3R)-3,4-dihydro-2H,2'H-3,6'-bichromene substituted by two methyl groups at positions 2' and 2' and hydroxy groups at positions 5' and 7 respectively. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
| Flora | Rank | Flora Definition | Family | Family Definition |
|---|
| Phaseolus | genus | A plant genus in the family FABACEAE which is the source of edible beans and the lectin PHYTOHEMAGGLUTININS.[MeSH] | Fabaceae | The large family of plants characterized by pods. Some are edible and some cause LATHYRISM or FAVISM and other forms of poisoning. Other species yield useful materials like gums from ACACIA and various LECTINS like PHYTOHEMAGGLUTININS from PHASEOLUS. Many of them harbor NITROGEN FIXATION bacteria on their roots. Many but not all species of beans belong to this family.[MeSH] |
| Phaseolus vulgaris | species | The plant species that provides kidney beans.[MeSH] | Fabaceae | The large family of plants characterized by pods. Some are edible and some cause LATHYRISM or FAVISM and other forms of poisoning. Other species yield useful materials like gums from ACACIA and various LECTINS like PHYTOHEMAGGLUTININS from PHASEOLUS. Many of them harbor NITROGEN FIXATION bacteria on their roots. Many but not all species of beans belong to this family.[MeSH] |
Cross-References
Synonyms (18)
| Synonym |
|---|
| (-)-phaseollinisoflavan |
| 40323-57-7 |
| phaseolinisoflavan |
| CHEMBL465812 |
| phaseollinisoflavan |
| chebi:109 , |
| LMPK12080014 |
| 6-[(3r)-7-hydroxy-3,4-dihydro-2h-chromen-3-yl]-2,2-dimethylchromen-5-ol |
| (3,6'-bi-2h-1-benzopyran)-5',7-diol, 3,4-dihydro-2',2'-dimethyl-, (r)- |
| 3a9f71823m , |
| phaseollin (isoflavan) |
| unii-3a9f71823m |
| (3r)-2',2'-dimethyl-3,4-dihydro-2h,2'h-3,6'-bichromene-5',7-diol |
| (3,6'-bi-2h-1-benzopyran)-5',7-diol, 3,4-dihydro-2',2'-dimethyl-, (3r)- |
| DTXSID60193326 , |
| dtxcid70115817 |
| Q27105239 |
| XP161674 |
Roles (1)
| Role | Description |
|---|
| plant metabolite | Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms. |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Drug Classes (1)
| Class | Description |
|---|
| hydroxyisoflavans | A member of the class of isoflavans in which one or more ring hydrogens are replaced by hydroxy groups. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Bioassays (6)
| Assay ID | Title | Year | Journal | Article |
|---|
| AID398785 | Antibacterial activity against Klebsiella pneumoniae ATCC 10031 at 100 mcg/ml by agar-dilution streak method | | | |
| AID398789 | Antifungal activity against Candida albicans ATCC 10231 at 100 mcg/ml by agar-dilution streak method | | | |
| AID398788 | Antibacterial activity against Mycobacterium smegmatis ATCC 607 at 100 mcg/ml by agar-dilution streak method | | | |
| AID398781 | Antibacterial activity against Escherichia coli ATCC 9637 at 100 mcg/ml by agar-dilution streak method | | | |
| AID398784 | Antibacterial activity against Salmonella gallinarum ATCC 9184 at 100 mcg/ml by agar-dilution streak method | | | |
| AID398779 | Antibacterial activity against Staphylococcus aureus ATCC 13709 by agar-dilution streak method | | | |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Research
Studies (4)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.80
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 12.80 (24.57) | | Research Supply Index | 1.79 (2.92) | | Research Growth Index | 4.59 (4.65) | | Search Engine Demand Index | 0.00 (26.88) | | Search Engine Supply Index | 0.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |