Compounds > (n-(p-cyanophenyl)-n'-(diphenylmethyl)guanidine)acetic acid
Page last updated: 2024-12-05
(n-(p-cyanophenyl)-n'-(diphenylmethyl)guanidine)acetic acid
Description
The compound you're describing is actually not a single molecule, but rather a general structure with the following features:
* **Guanidine:** A functional group with the formula HN=C(NH2)2. It is known for its ability to form strong hydrogen bonds and can act as a base.
* **Phenyl group:** A benzene ring (C6H6). In this case, it is substituted with a cyano group (-CN), making it a **p-cyanophenyl** group.
* **Diphenylmethyl:** A benzyl group (C6H5CH2-) with an additional phenyl group attached, leading to a structure with two phenyl groups attached to a CH group.
* **Acetic acid:** A carboxylic acid with the formula CH3COOH.
The exact arrangement of these groups within the compound you mentioned is not clear from the description. However, based on the name and structure, it is likely a molecule where the guanidine group is connected to a p-cyanophenyl group on one side and a diphenylmethyl group on the other side. This structure is then attached to an acetic acid group.
**Why this type of compound might be important for research:**
* **Pharmacological activity:** Guanidine derivatives are often studied for their potential pharmacological properties. They can act as inhibitors of various enzymes, including those involved in signal transduction pathways. The combination of the guanidine group with the specific substituents (p-cyanophenyl and diphenylmethyl) might give this compound unique biological activity.
* **Materials science:** The compound's structure features aromatic rings (phenyl groups) and potentially a polar carboxylic acid group. This combination could make it useful in developing materials with specific properties, such as conductivity, luminescence, or mechanical strength.
* **Chemical synthesis:** The presence of a guanidine group and different aromatic substituents makes this compound a potential starting material or intermediate for the synthesis of other complex molecules with various functionalities.
**To know more about the specific importance of this compound for research, you would need further details:**
* **Exact structure:** The precise arrangement of the different groups is crucial.
* **Properties:** Information about its solubility, stability, and reactivity would help understand its potential applications.
* **Biological activity:** Studies on its interactions with biological targets (e.g., enzymes, receptors) would be necessary to assess its pharmacological significance.
Ultimately, the importance of this specific compound depends on its unique properties and potential applications, which require further investigation.
NC 174: a trisubstituted guanidine high potency sweetener; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
[N-(4-cyanophenyl)-N'-(diphenylmethyl)guanidine]acetic acid : A trisubstituted guanidine, carrying 4-cyanophenyl, diphenylmethyl and carboxymethyl substituents, which is known to act as a highly potent sweetening agent. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
Cross-References
Synonyms (33)
| Synonym |
|---|
| n-(((4-cyanophenyl)amino)((diphenylmethyl)amino)methylene)glycine |
| glycine, n-(((4-cyanophenyl)amino)((diphenylmethyl)amino)methylene)- |
| (n-(p-cyanophenyl)-n'-(diphenylmethyl)guanidine)acetic acid |
| nc174 |
| n-(p-cyanophenyl)-n'-diphenylmethyl-guanidine-acetic acid |
| GAS , |
| nc 174 |
| n-(4-cyanophenyl)-n'-(diphenylmethyl)guanidineacetic acid |
| CHEBI:385425 , |
| nc-174 |
| 138460-25-0 |
| n-(p-cyanophenyl)-n'-(diphenylmethyl)-n''-(carboxymethyl)guanidine |
| 2-[[(benzhydrylamino)-[(4-cyanophenyl)amino]methylidene]amino]ethanoic acid |
| cp-dpm-ga |
| (z)-n-{[(4-cyanophenyl)amino][(diphenylmethyl)amino]methylidene}glycine |
| [n-(4-cyanophenyl)-n'-(diphenylmethyl)guanidine]acetic acid |
| DB07816 |
| CHEMBL170077 |
| 2-[[(benzhydrylamino)-(4-cyanoanilino)methylidene]amino]acetic acid |
| EPITOPE ID:161503 |
| n-{[(4-cyanophenyl)amino][(diphenylmethyl)amino]methylene}glycine |
| (e)-n-{[(4-cyanophenyl)amino][(diphenylmethyl)amino]methylidene}glycine |
| n-{(4-cyanoanilino)[(diphenylmethyl)amino]methylidene}glycine |
| DTXSID70930123 |
| Q27097026 |
| glycine, n-(((4-cyanophenyl)amino)((diphenylmethyl)amino)methylene)-, (n(z))- |
| unii-mw7j9su4jq |
| 1808181-85-2 |
| (n(z))-n-(((4-cyanophenyl)amino)((diphenylmethyl)amino)methylene)glycine |
| mw7j9su4jq , |
| PD004984 |
| AKOS040753224 |
| glycine, n-[[(4-cyanophenyl)amino][(diphenylmethyl)amino]methylene]- |
Roles (2)
| Role | Description |
|---|
| epitope | The biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds. |
| sweetening agent | Substance that sweeten food, beverages, medications, etc. |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Drug Classes (2)
| Class | Description |
|---|
| glycine derivative | A proteinogenic amino acid derivative resulting from reaction of glycine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom. |
| guanidines | Any organonitrogen compound containing a carbamimidamido (guanidino) group. Guanidines have the general structure (R(1)R(2)N)(R(3)R(4)N)C=N-R(5) and are related structurally to amidines and ureas. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Research
Studies (16)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (81.25) | 18.2507 |
| 2000's | 3 (18.75) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 11.21
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 11.21 (24.57) | | Research Supply Index | 2.94 (2.92) | | Research Growth Index | 4.15 (4.65) | | Search Engine Demand Index | 0.00 (26.88) | | Search Engine Supply Index | 0.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 18 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |