Page last updated: 2024-12-09

2,2'-methylenebis(1,3-cyclohexanedione)

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

2,2'-methylenebis(1,3-cyclohexanedione): an inhibitor of apoptosis (programmed cell death) [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

apoptosis inhibitor : Any substance that inhibits the process of apoptosis (programmed cell death) in multi-celled organisms. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID2748618
CHEBI ID108604
SCHEMBL ID598863
MeSH IDM0427169

Synonyms (31)

Synonym
BRD-K00676343-001-01-6
2-[(2,6-dioxocyclohexyl)methyl]cyclohexane-1,3-dione
ENAMINE_000755 ,
HSCI1_000071
apoptosis inhibitor
m50054
CHEBI:108604
HMS1396C07
AKOS001027108
2,2'-methylenebis(1,3-cyclohexanedione)
unii-np899ea5d8
einecs 258-989-1
2,2'-methylenebis(cyclohexane-1,3-dione)
54135-60-3
np899ea5d8 ,
SCHEMBL598863
AB01097539-03
2,2'-methylenedicyclohexane-1,3-dione
Q27187525
DTXSID50202476
sr-01000027601
SR-01000027601-1
Z56778068
2,2'-methylenedi-1,3-cyclohexanedione
mfcd00192291
A13058
NCGC00325175-01
1,3-cyclohexanedione, 2,2'-methylenedi-
1,3-cyclohexanedione, 2,2'-methylenebis-
HY-103347
CS-0027696
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
beta-diketoneA diketone in which the two keto groups are separated by a single carbon atom.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID588519A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities2011Antiviral research, Sep, Volume: 91, Issue:3
High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's3 (50.00)24.3611
2020's1 (16.67)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.56

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.56 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.51 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.56)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]