butanol dehydrogenase (NAD+) activity

Definition

Target type: molecularfunction

Catalysis of the reaction: butan-1-ol + NAD+ = butanal + H+ + NADH. [GOC:mengo_curators, PMID:1999395, RHEA:33199]

Butanol dehydrogenase (NAD+) is an enzyme that catalyzes the reversible oxidation of butanol to butyraldehyde, using NAD+ as an electron acceptor. This enzyme plays a crucial role in the metabolism of butanol, a four-carbon alcohol that is a key component of biofuels. The reaction catalyzed by butanol dehydrogenase involves the transfer of two electrons and two protons from butanol to NAD+, converting NAD+ to NADH. This reaction is highly specific for butanol and NAD+, and it is inhibited by a number of compounds, including ethanol and propanol. Butanol dehydrogenase is found in a variety of organisms, including bacteria, yeast, and mammals. In bacteria, this enzyme is involved in the production of butanol as a biofuel. In yeast, it is involved in the breakdown of butanol during fermentation. In mammals, butanol dehydrogenase is involved in the detoxification of butanol and its metabolism into other compounds. This enzyme is also involved in the synthesis of certain fatty acids and other important molecules.'
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Proteins (1)

Compounds (4)