Target type: molecularfunction
Catalysis of the reaction: H2O + scopolin = beta-D-glucose + scopoletin. [EC:3.2.1.21, GOC:pz]
Scopolin beta-glucosidase activity refers to the enzymatic hydrolysis of scopolin, a flavonoid glycoside, to release glucose and scopoletin. Scopolin beta-glucosidase is a hydrolase that specifically cleaves the beta-glycosidic bond between glucose and scopoletin. This enzymatic activity is crucial in the metabolism of scopolin, a compound with various pharmacological properties, including antioxidant, anti-inflammatory, and neuroprotective effects. In plants, scopolin beta-glucosidase plays a role in the biosynthesis and detoxification of scopoletin. It is involved in the conversion of scopolin to scopoletin, which acts as a signaling molecule and defense compound. In addition, scopolin beta-glucosidase may contribute to the regulation of plant growth and development. The enzyme's activity can be influenced by various factors, including pH, temperature, and the presence of inhibitors. Scopolin beta-glucosidase activity has been studied in various plant species, including tobacco, ginseng, and apple. Research on this enzyme provides insights into the role of flavonoid metabolism in plant physiology and the development of novel therapeutic strategies based on the pharmacological properties of scopoletin.'
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| Protein | Definition | Taxonomy |
|---|---|---|
| Cytosolic beta-glucosidase | A cytosolic beta-glucosidase that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q9H227] | Homo sapiens (human) |
| Compound | Definition | Classes | Roles |
|---|---|---|---|
| 1-deoxynojirimycin | 1-deoxy-nojirimycin: structure in first source duvoglustat : An optically active form of 2-(hydroxymethyl)piperidine-3,4,5-triol having 2R,3R,4R,5S-configuration. | 2-(hydroxymethyl)piperidine-3,4,5-triol; piperidine alkaloid | anti-HIV agent; anti-obesity agent; bacterial metabolite; EC 3.2.1.20 (alpha-glucosidase) inhibitor; hepatoprotective agent; hypoglycemic agent; plant metabolite |
| 2,5-dideoxy-2,5-imino-d-glucitol | 2,5-dideoxy-2,5-imino-D-glucitol: structure in first source | ||
| validamine | validamine : An amino cyclitol consisting of 1D-chiro-inositol lacking the 6-hydroxy group and having those at positions 1 and 5 replaced by amino and hydroxymethyl groups respectively. validamine: RN given from CA Index Guide; RN not in Chemline 11/84; structure given in first source | amino cyclitol |