Target type: molecularfunction
Catalysis of the reaction: S-adenosyl-L-methionine + a thiopurine = S-adenosyl-L-homocysteine + a thiopurine S-methylether. [EC:2.1.1.67]
| Protein | Definition | Taxonomy |
|---|---|---|
| Thiopurine S-methyltransferase | A thiopurine S-methyltransferase that is encoded in the genome of human. [PRO:DNx, UniProtKB:P51580] | Homo sapiens (human) |
| Thiopurine S-methyltransferase | A thiopurine S-methyltransferase that is encoded in the genome of human. [PRO:DNx, UniProtKB:P51580] | Homo sapiens (human) |
| Compound | Definition | Classes | Roles |
|---|---|---|---|
| 4-hydroxybenzoic acid | 4-hydroxybenzoic acid : A monohydroxybenzoic acid that is benzoic acid carrying a hydroxy substituent at C-4 of the benzene ring. | monohydroxybenzoic acid | algal metabolite; plant metabolite |
| 3-chlorobenzoic acid | monochlorobenzoic acid | drug metabolite | |
| 4-aminobenzoic acid | 4-aminobenzoic acid : An aminobenzoic acid in which the amino group is para to the carboxy group. 4-Aminobenzoic Acid: An aminobenzoic acid isomer that combines with pteridine and GLUTAMIC ACID to form FOLIC ACID. The fact that 4-aminobenzoic acid absorbs light throughout the UVB range has also resulted in its use as an ingredient in SUNSCREENS. 4-ammoniobenzoate : A zwitterion obtained by transfer of a proton from the carboxy to the amino group of 4-aminobenzoic acid. | aminobenzoic acid; aromatic amino-acid zwitterion | allergen; Escherichia coli metabolite; plant metabolite |
| 4-nitrobenzoic acid | 4-nitrobenzoic acid : A nitrobenzoic acid having the nitro group at the 4-position. 4-nitrobenzoic acid: RN given refers to parent cpd | nitrobenzoic acid | |
| 4-chlorobenzoic acid | 4-chlorobenzoic acid : A monochlorobenzoic acid carrying a chloro substituent at position 4. 4-chlorobenzoic acid: RN given refers to parent cpd | monochlorobenzoic acid | bacterial xenobiotic metabolite |
| veratric acid | 3,4-dimethoxybenzoic acid : A member of the class of benzoic acids that is benzoic acid substituted by methoxy groups at positions 2 and 3. veratric acid: RN given refers to parent cpd; structure | benzoic acids | allergen; plant metabolite |
| 4-tert-butylbenzoic acid | 4-tert-butylbenzoic acid: RN given refers to parent cpd | alkylbenzene | |
| 3-toluic acid | 3-toluic acid: RN given refers to parent cpd; structure | methylbenzoic acid | human xenobiotic metabolite |
| 3,5-dinitrobenzoic acid | 3,5-dinitrobenzoic acid : A member of the class of benzoic acids that is benzoic acid in which the hydrogens at positions 3 and 5 are replaced by nitro groups. | benzoic acids; C-nitro compound | |
| 4-toluic acid | 4-toluic acid: RN given refers to parent cpd; structure p-toluic acid : A methylbenzoic acid in which the methyl substituent is located at position 4. | methylbenzoic acid | |
| 4-anisic acid | 4-methoxybenzoic acid : A methoxybenzoic acid substituted with a methoxy group at position C-4. 4-methoxybenzoic acid: structure in first source | methoxybenzoic acid | plant metabolite |
| vanillic acid | vanillic acid : A monohydroxybenzoic acid that is 4-hydroxybenzoic acid substituted by a methoxy group at position 3. Vanillic Acid: A flavoring agent. It is the intermediate product in the two-step bioconversion of ferulic acid to vanillin. (J Biotechnol 1996;50(2-3):107-13). | methoxybenzoic acid; monohydroxybenzoic acid | plant metabolite |
| 3-nitrobenzoic acid | 3-nitrobenzoic acid: RN given refers to parent cpd | ||
| carzenide | sulfonamide | ||
| 3,5-dimethylbenzoic acid | 3,5-dimethylbenzoic acid : A dimethylbenzoic acid in which the two methyl groups are located at positions 3 and 5. | dimethylbenzoic acid | |
| 3-methoxybenzoic acid | methoxybenzoic acid | flavouring agent; human urinary metabolite | |
| isovanillic acid | 3-hydroxy-4-methoxybenzoic acid : A methoxybenzoic acid that is 4-methoxybenzoic acid bearing a hydroxy substituent at position 3. | methoxybenzoic acid; monohydroxybenzoic acid | antibacterial agent; plant metabolite |
| sinefungin | adenosines; non-proteinogenic alpha-amino acid | antifungal agent; antimicrobial agent | |
| 3,4-dimethoxy-5-hydroxybenzoic acid | 3,4-dimethoxy-5-hydroxybenzoic acid: thiopurine methyltransferase inhibitor | trihydroxybenzoic acid | |
| 3,5-dihydroxy-4-methoxybenzoic acid | 3,5-dihydroxy-4-methoxybenzoic acid: catechol methyltransferase inhibitor; N1 same as NM | trihydroxybenzoic acid |