Target type: biologicalprocess
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus. [GOC:mah]
Cellular response to sucrose stimulus is a complex process involving multiple signaling pathways and cellular mechanisms. When sucrose is sensed by cells, it triggers a cascade of events that ultimately lead to changes in gene expression, metabolism, and cellular behavior. The process can be broadly divided into the following stages:
1. **Sucrose Perception:** The first step involves the detection of sucrose by specific receptors on the cell surface. These receptors can be transmembrane proteins or enzymes that bind to sucrose with high affinity. Different cell types may utilize different types of sucrose receptors.
2. **Signal Transduction:** Upon sucrose binding, the receptor triggers a series of downstream signaling events, including phosphorylation cascades and activation of second messengers like calcium ions. These signaling pathways can vary depending on the cell type and the specific receptor involved.
3. **Gene Regulation:** The signaling cascades ultimately lead to changes in gene expression. This can involve the activation or repression of specific genes involved in various cellular functions, including metabolism, transport, and growth.
4. **Metabolic Regulation:** Sucrose is a major source of energy and carbon for cells. Upon sensing sucrose, cells activate pathways that allow for the efficient uptake, transport, and metabolism of sucrose. This includes the induction of enzymes involved in sucrose breakdown and utilization.
5. **Cellular Response:** The changes in gene expression and metabolism ultimately result in cellular responses to the sucrose stimulus. These responses can include:
- **Growth and Development:** Sucrose can promote cell growth and division by providing the necessary nutrients and energy.
- **Transport and Storage:** Sucrose can stimulate the transport and storage of nutrients and energy reserves.
- **Stress Response:** In some cases, sucrose can trigger stress responses, such as the production of reactive oxygen species.
- **Signaling and Communication:** Sucrose can act as a signaling molecule, triggering the release of hormones and other signaling molecules.
The cellular response to sucrose stimulus is highly regulated and varies depending on the cell type, the concentration of sucrose, and other environmental factors. It plays a crucial role in various biological processes, including plant growth and development, nutrient uptake, and energy metabolism.'
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Protein | Definition | Taxonomy |
---|---|---|
Calcitonin gene-related peptide type 1 receptor | A calcitonin gene-related peptide type 1 receptor that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q16602] | Homo sapiens (human) |
Compound | Definition | Classes | Roles |
---|---|---|---|
haloperidol | haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety. Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279) | aromatic ketone; hydroxypiperidine; monochlorobenzenes; organofluorine compound; tertiary alcohol | antidyskinesia agent; antiemetic; dopaminergic antagonist; first generation antipsychotic; serotonergic antagonist |
azaperone | azaperone : An N-arylpiperazine that is 2-(piperazin-1-yl)pyridine in which the amino hydrogen is replaced by a 3-(4-fluobenzoyl)propyl group. Used mainly as a tranquiliser for pigs and elephants. Azaperone: A butyrophenone used in the treatment of PSYCHOSES. | aminopyridine; aromatic ketone; monofluorobenzenes; N-alkylpiperazine; N-arylpiperazine; tertiary amino compound | antipsychotic agent; dopaminergic antagonist |
telcagepant | telcagepant: structure in first source | ||
mk 3207 | |||
bms 694153 | |||
(5s,6s,9r)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5h-cyclohepta(b)pyridin-9-yl 4-(2-oxo-2,3-dihydro-1h-imidazo(4,5-b)pyridin-1-yl)piperidine-1-carboxylate | |||
mk-8825 | |||
atogepant | atogepant : A secondary carboxamide resulting from the formal condensation of the carboxy group of (3'S)-2'-oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-carboxylic acid with the amino group of (3S,5S,6R)-3-amino-6-methyl-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)piperidin-2-one. It is a selective oral, small-molecule antagonist of calcitonin gene-related peptide (CGRP) receptor that has been approved for the treatment of migraine. | azaspiro compound; organic heterotetracyclic compound; piperidones; secondary carboxamide; trifluorobenzene | calcitonin gene-related peptide receptor antagonist |