Target type: biologicalprocess
Any process that modulates the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth. [GOC:dph]
| Protein | Definition | Taxonomy |
|---|---|---|
| Sonic hedgehog protein | A sonic hedgehog protein that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q15465] | Homo sapiens (human) |
| Compound | Definition | Classes | Roles |
|---|---|---|---|
| jervine | jervine: teratogen from Veratrum grandiflorum; RN given refers to parent cpd(3beta,23beta)-isomer; structure | piperidines | |
| cyclopamine | piperidines | glioma-associated oncogene inhibitor | |
| cur 61414 | CUR 61414: inhibits the hedehog signaling pathway; structure in first source | ||
| gdc 0449 | HhAntag691: inhibits the hedgehog pathway and ABC transporters; has antineoplastic activity | benzamides; monochlorobenzenes; pyridines; sulfone | antineoplastic agent; Hedgehog signaling pathway inhibitor; SMO receptor antagonist; teratogenic agent |
| robotnikinin | robotnikinin: binds sonic hedgehog protein to block its signaling pathway; structure in first source |