L-serine transport

Definition

Target type: biologicalprocess

The directed movement of L-serine, the L-enantiomer of 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai, GOC:jsg, GOC:mah]

L-serine transport is a crucial biological process that involves the movement of L-serine, an essential amino acid, across cell membranes. This process is vital for maintaining cellular homeostasis and supporting various metabolic pathways. L-serine transport occurs via specialized membrane proteins known as L-serine transporters. These proteins facilitate the selective uptake and release of L-serine into and out of cells. The transport mechanism can be active or passive, depending on the specific transporter and the cellular environment. Active transport requires energy to move L-serine against its concentration gradient, whereas passive transport relies on the concentration gradient to drive the movement. Several types of L-serine transporters have been identified in different organisms, including bacteria, yeast, and mammals. These transporters exhibit varying substrate specificity and transport kinetics, reflecting the diverse roles of L-serine in different cellular contexts. L-serine is involved in various metabolic pathways, including protein synthesis, glutathione synthesis, and the synthesis of other amino acids. The transport of L-serine is tightly regulated to ensure an appropriate intracellular concentration of this essential amino acid. This regulation involves factors such as substrate availability, hormonal signals, and the activity of specific regulatory proteins. Disruptions in L-serine transport can have significant consequences for cellular function and organismal health. For instance, defects in L-serine transporters can lead to metabolic disorders and neurological abnormalities.'
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Proteins (2)

Compounds (8)