Target type: biologicalprocess
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus. [GOC:hb]
Response to temperature stimulus is a fundamental biological process that enables organisms to survive and thrive in a constantly changing environment. It involves a complex interplay of cellular and molecular mechanisms that allow organisms to sense, transduce, and respond to temperature fluctuations.
The process begins with the detection of temperature changes by specialized sensory receptors called thermosensors. These receptors can be found in various locations throughout the body, including the skin, internal organs, and even within cells. Thermosensors are typically ion channels or G protein-coupled receptors that undergo conformational changes in response to temperature fluctuations.
Upon sensing a temperature change, thermosensors initiate a signaling cascade that involves a series of intracellular events. This cascade can include the activation of downstream signaling pathways, the production of second messengers, and the alteration of gene expression.
The ultimate response to a temperature stimulus is highly dependent on the specific organism and the nature of the temperature change. In general, organisms can respond to temperature fluctuations in a variety of ways, including:
- **Behavioral responses:** Organisms may move to cooler or warmer environments, seek shade or sunlight, or alter their activity levels.
- **Physiological responses:** Organisms may adjust their metabolic rate, alter their blood flow, or produce heat-shock proteins to protect their cells.
- **Developmental responses:** Some organisms may undergo developmental changes in response to temperature, such as diapause in insects or seed germination in plants.
Temperature response mechanisms are crucial for maintaining homeostasis and ensuring survival. They allow organisms to adapt to a wide range of environmental temperatures, from the freezing arctic to the scorching desert.
For example, cold-blooded organisms, such as reptiles and amphibians, rely heavily on behavioral responses to regulate their body temperature. They may bask in the sun to warm up or seek shade to cool down. In contrast, warm-blooded organisms, such as mammals and birds, have developed sophisticated physiological mechanisms to maintain a stable internal temperature, regardless of the external environment.
The study of response to temperature stimulus is an active area of research in biology and medicine. Understanding these mechanisms can provide insights into a wide range of physiological processes, including disease pathogenesis and drug development.'
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Protein | Definition | Taxonomy |
---|---|---|
ATP-dependent Clp protease proteolytic subunit | An ATP-dependent Clp protease proteolytic subunit that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0A6G7] | Escherichia coli K-12 |
Transient receptor potential cation channel subfamily V member 2 | A transient receptor potential cation channel TRPV2 that is encoded in the genome of human. [PRO:CNA, UniProtKB:Q9Y5S1] | Homo sapiens (human) |
Transient receptor potential cation channel subfamily V member 3 | A transient receptor potential cation channel TRPV3 that is encoded in the genome of human. [PRO:CNA, UniProtKB:Q8NET8] | Homo sapiens (human) |
Compound | Definition | Classes | Roles |
---|---|---|---|
2-aminoethoxydiphenyl borate | 2-aminoethoxydiphenyl borate: is a novel membrane-penetrable modulator and transient receptor potential channel blocker; structure in first source; do not confuse with 2-APB cpd 2-aminoethoxydiphenylborane : An organoboron compound that is diphenylborane in which the borane hydrogen is replaced by a 2-aminoethoxy group. | organoboron compound; primary amino compound | calcium channel blocker; IP3 receptor antagonist; potassium channel opener |
cannabinol | Cannabinol: A physiologically inactive constituent of Cannabis sativa L. | dibenzopyran | |
cannabichromene | 1-benzopyran | ||
(6ar-trans)-isomer of tetrahydrocannabivarin 9 | |||
camphora | (R)-camphor : The (R)- enantiomer of camphor. camphora: a component of Guanxingao, a kind of traditional Chinese rubber electuary medicine which is able to either cure or guard against coronary heart disease and angina pectoris | camphor | |
carbobenzyloxyleucyl-tyrosine chloromethyl ketone | |||
hc 030031 | 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide: a TRPA1 channel blocker | ||
tranilast | tranilast : An amidobenzoic acid that is anthranilic acid in which one of the anilino hydrogens is replaced by a 3,4-dimethoxycinnamoyl group. tranilast: antiallergic drug; potent inhibitor of homologous passive cutaneous anaphylaxis | amidobenzoic acid; cinnamamides; dimethoxybenzene; secondary carboxamide | anti-allergic agent; anti-asthmatic drug; antineoplastic agent; aryl hydrocarbon receptor agonist; calcium channel blocker; hepatoprotective agent; nephroprotective agent |
cannabigerol | cannabigerol : A member of the class of resorcinols that is resorcinol which is substituted by a (2E)-3,7-dimethylocta-2,6-dien-1-yl group at position 2 and by a pentyl group at position 5. It is a natural product found in Cannabis sativa and Helichrysum species. cannabigerol: RN given refers to (E)-isomer; structure given in first source | phytocannabinoid; resorcinols | anti-inflammatory agent; antibacterial agent; antioxidant; appetite enhancer; cannabinoid receptor agonist; neuroprotective agent; plant metabolite |
sclerotiamide | sclerotiamide: related to the paraherquamides; isolated from the sclerotia of Aspergillus sclerotiorum; structure given in first source | ||
cannabidivarin | cannabidivarin: from Cannabis sativa | monoterpenoid |