Any compound that acts as an agonist towards the liver X receptors.
ChEBI ID: 86029
| Member | Definition | Class |
|---|---|---|
| 24,25-epoxycholesterol | A 3beta-hydroxy-Delta(5)-steroid that is desmosterol in which the double bond at position 24-25 has been oxidised to the corresponding epoxide (the 24S diastereoisomer). It is an oxysterol agonist of the liver X receptor. | 24(S),25-epoxycholesterol |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 9 (14.29) | 18.7374 |
| 1990's | 5 (7.94) | 18.2507 |
| 2000's | 28 (44.44) | 29.6817 |
| 2010's | 17 (26.98) | 24.3611 |
| 2020's | 4 (6.35) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 7 (10.77%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 58 (89.23%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Oxysterols receptor LXR-alpha | Homo sapiens (human) | EC50 | 2.7786 | 9 | 9 |
| Oxysterols receptor LXR-beta | Homo sapiens (human) | EC50 | 5.2135 | 4 | 4 |