A compound that exhibits agonist activity at the P2Y2 receptor.
ChEBI ID: 53142
| Member | Definition | Class |
|---|---|---|
| diquafosol | A pyrimidine ribonucleoside 5'-tetraphosphate compound having 5'-uridinyl residues at the P(1)- and P(4)-positions. | P(1),P(4)-bis(uridin-5'-yl) tetraphosphate |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (0.84) | 18.2507 |
| 2000's | 25 (21.01) | 29.6817 |
| 2010's | 72 (60.50) | 24.3611 |
| 2020's | 21 (17.65) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 38 (30.16%) | 5.53% |
| Reviews | 20 (15.87%) | 6.00% |
| Case Studies | 1 (0.79%) | 4.05% |
| Observational | 4 (3.17%) | 0.25% |
| Other | 63 (50.00%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| P2Y purinoceptor 1 | Homo sapiens (human) | EC50 | 20.0000 | 1 | 1 |
| P2Y purinoceptor 2 | Homo sapiens (human) | EC50 | 74.5589 | 16 | 16 |
| P2Y purinoceptor 4 | Homo sapiens (human) | EC50 | 0.1300 | 2 | 2 |
| P2Y purinoceptor 6 | Homo sapiens (human) | EC50 | 10.5800 | 2 | 2 |