Roles > EC 1.4.3.22 (diamine oxidase) inhibitor
Page last updated: 2024-08-05 15:33:14
EC 1.4.3.22 (diamine oxidase) inhibitor
An EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor that interferes with the action of diamine oxidase (EC 1.4.3.22).
ChEBI ID: 53659
Members (1)
| Member | Definition | Class |
|---|
| bulbocapnine | An aporphine alkaloid that has been isolated from Corydalis and exhibits inhibitory activity against enzymes such as tyrosine 3-monooxygenase and diamine oxidase. | bulbocapnine |
Research
Studies (51)
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|
| pre-1990 | 38 (74.51) | 18.7374 |
| 1990's | 7 (13.73) | 18.2507 |
| 2000's | 2 (3.92) | 29.6817 |
| 2010's | 4 (7.84) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Study Types
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 2 (3.23%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 60 (96.77%) | 84.16% |
Protein Targets (2)
Inhibition Measurements
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| D | Rattus norvegicus (Norway rat) | IC50 | 0.7395 | 2 | 2 |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | IC50 | 14.0235 | 2 | 2 |