Pathways > ergothioneine biosynthesis I (bacteria)
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ergothioneine biosynthesis I (bacteria)
Proteins (5)
| Protein | Synonyms | Taxonomy |
|---|
| Histidine N-alpha-methyltransferase | EC 2.1.1.44; Histidine trimethyltransferase | Mycolicibacterium smegmatis MC2 155 |
| Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase | EC 3.5.1.118; Gamma-glutamyl hercynylcysteine S-oxide hydrolase | Mycolicibacterium smegmatis MC2 155 |
| Hercynine oxygenase | EC 1.14.99.50; Gamma-glutamyl hercynylcysteine S-oxide synthase | Mycolicibacterium smegmatis MC2 155 |
| Probable hercynylcysteine sulfoxide lyase | EC 4.4.-.- | Mycolicibacterium smegmatis MC2 155 |
| Glutamate--cysteine ligase EgtA | EC 6.3.2.2; Gamma-glutamylcysteine synthetase; GCS; Gamma-ECS | Mycolicibacterium smegmatis MC2 155 |
Compounds (14)
| Compound | Description |
|---|
| hydronium ion | |
| Ammonium | |
| iron | A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN. |
| Orthophosphate | |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| Pyruvic Acid | An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed) |
| ergothioneine | A naturally occurring metabolite of HISTIDINE that has antioxidant properties. |
| hercynine | structure |
| glutamate | |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| Cysteine | A thiol-containing non-essential amino acid that is oxidized to form CYSTINE. |
| s-adenosylmethionine | Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed) |