diphthamide biosynthesis

Proteins (1)

Protein	Synonyms	Taxonomy
Diphthine--ammonia ligase	EC 6.3.1.14; ATP-binding domain-containing protein 4; Diphthamide synthase; Diphthamide synthetase; Protein DPH6 homolog	Homo sapiens (human)

Compound	Description
diphosphoric acid
hydronium ion
Ammonium
adenosine monophosphate	Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
5'-methylthioadenosine	structure
adenosine triphosphate	An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
s-adenosylmethionine	Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)