diphthamide biosynthesis I (archaea)

Proteins (2)

Protein	Synonyms	Taxonomy
2-(3-amino-3-carboxypropyl)histidine synthase	EC 2.5.1.108; Diphthamide biosynthesis protein Dph2; S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase	Pyrococcus horikoshii OT3
Diphthine synthase	EC 2.1.1.98; Diphthamide biosynthesis methyltransferase	Pyrococcus horikoshii OT3

Compound	Description
diphosphoric acid
hydronium ion
Ammonium
adenosine monophosphate	Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
5'-methylthioadenosine	structure
adenosine triphosphate	An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
s-adenosylmethionine	Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)