Page last updated: 2024-10-06

Valproic acid pathway

Proteins (0)

Compounds (11)

CompoundDescription
gamma-aminobutyric acidThe most common inhibitory neurotransmitter in the central nervous system.
valproic acidA fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
uridine diphosphateA uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.
2-propyl-4-pentenoic acidputative toxic metabolite of valproic acid
5-hydroxyvalproate
uridine diphosphate glucuronic acidA nucleoside diphosphate sugar which serves as a source of glucuronic acid for polysaccharide biosynthesis. It may also be epimerized to UDP iduronic acid, which donates iduronic acid to polysaccharides. In animals, UDP glucuronic acid is used for formation of many glucosiduronides with various aglycones.
2-propyl-2,4-pentadienoic acidtoxic metabolite of valproic acid; RN given refers to cpd without isomeric designation
4-hydroxyvalproateRN given refers to compound with no isomeric designation
2-n-propyl-3-oxopentanoic acidstructure given in first source
valproic acid glucuronidemajor metabolite of valproic acid
propionyl-coenzyme aRN given refers to parent cpd