Page last updated: 2024-10-06

Regulation of necroptotic cell death

Proteins (19)

ProteinSynonymsTaxonomy
E3 ubiquitin-protein ligase parkinParkin; EC 2.3.2.31; Parkin RBR E3 ubiquitin-protein ligase; Parkinson juvenile disease protein 2; Parkinson disease protein 2Homo sapiens (human)
Flotillin-1Homo sapiens (human)
Heat shock protein HSP 90-alphaEC 3.6.4.10; Heat shock 86 kDa; HSP 86; HSP86; Lipopolysaccharide-associated protein 2; LAP-2; LPS-associated protein 2; Renal carcinoma antigen NY-REN-38Homo sapiens (human)
Caspase-8CASP-8; EC 3.4.22.61; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; MACHHomo sapiens (human)
Receptor-interacting serine/threonine-protein kinase 1EC 2.7.11.1; Cell death protein RIP; Receptor-interacting protein 1; RIP-1Homo sapiens (human)
E3 ubiquitin-protein ligase Itchy homologItch; EC 2.3.2.26; Atrophin-1-interacting protein 4; AIP4; HECT-type E3 ubiquitin transferase Itchy homolog; NFE2-associated polypeptide 1; NAPP1Homo sapiens (human)
Mixed lineage kinase domain-like proteinhMLKLHomo sapiens (human)
Receptor-interacting serine/threonine-protein kinase 3EC 2.7.11.1; RIP-like protein kinase 3; Receptor-interacting protein 3; RIP-3Homo sapiens (human)
Syntenin-1Melanoma differentiation-associated protein 9; MDA-9; Pro-TGF-alpha cytoplasmic domain-interacting protein 18; TACIP18; Scaffold protein Pbp1; Syndecan-binding protein 1Homo sapiens (human)
Hsp90 co-chaperone Cdc37Hsp90 chaperone protein kinase-targeting subunit; p50Cdc37Homo sapiens (human)
TNF receptor-associated factor 2EC 2.3.2.27; E3 ubiquitin-protein ligase TRAF2; RING-type E3 ubiquitin transferase TRAF2; Tumor necrosis factor type 2 receptor-associated protein 3Homo sapiens (human)
FAS-associated death domain proteinFAS-associating death domain-containing protein; Growth-inhibiting gene 3 protein; Mediator of receptor induced toxicity; Protein FADDHomo sapiens (human)
Ubiquitin-conjugating enzyme E2 L3EC 2.3.2.23; E2 ubiquitin-conjugating enzyme L3; L-UBC; UbcH7; Ubiquitin carrier protein L3; Ubiquitin-conjugating enzyme E2-F1; Ubiquitin-protein ligase L3Homo sapiens (human)
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunitEC 2.4.1.255; O-GlcNAc transferase subunit p110; O-linked N-acetylglucosamine transferase 110 kDa subunit; OGTHomo sapiens (human)
E3 ubiquitin-protein ligase CHIPEC 2.3.2.27; Antigen NY-CO-7; CLL-associated antigen KW-8; Carboxy terminus of Hsp70-interacting protein; RING-type E3 ubiquitin transferase CHIP; STIP1 homology and U box-containing protein 1Homo sapiens (human)
Flotillin-2Epidermal surface antigen; ESA; Membrane component chromosome 17 surface marker 1Homo sapiens (human)
Tumor necrosis factor receptor type 1-associated DEATH domain proteinTNFR1-associated DEATH domain protein; TNFRSF1A-associated via death domainHomo sapiens (human)
Programmed cell death 6-interacting proteinPDCD6-interacting protein; ALG-2-interacting protein 1; ALG-2-interacting protein X; Hp95Homo sapiens (human)
E3 ubiquitin-protein ligase pellino homolog 1Pellino-1; EC 2.3.2.27; Pellino-related intracellular-signaling molecule; RING-type E3 ubiquitin transferase pellino homolog 1Homo sapiens (human)

Compounds (4)

CompoundDescription
uridine diphosphateA uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
myo-inositol 1,3,4,5,6-pentakisphosphate
inositol-1,3,4,6-tetrakisphosphatefor cpd without numerical locants of phosphate groups, index INOSITOL PHOSPHATES