Pathways > Purine Nucleotides De Novo Biosynthesis 2
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Purine Nucleotides De Novo Biosynthesis 2

Proteins (29)

ProteinSynonymsTaxonomy
ATP synthase subunit aATP synthase F0 sector subunit a; F-ATPase subunit 6Escherichia coli K-12
Inosine-5'-monophosphate dehydrogenaseIMP dehydrogenase; IMPD; IMPDH; EC 1.1.1.205Escherichia coli K-12
Adenylosuccinate synthetaseAMPSase; AdSS; EC 6.3.4.4; IMP--aspartate ligaseEscherichia coli K-12
Adenylate kinaseAK; EC 2.7.4.3; ATP-AMP transphosphorylase; ATP:AMP phosphotransferase; Adenylate monophosphate kinaseEscherichia coli K-12
Adenylosuccinate lyaseASL; EC 4.3.2.2; Adenylosuccinase; ASaseEscherichia coli K-12
Phosphoribosylformylglycinamidine synthaseFGAM synthase; FGAMS; EC 6.3.5.3; Formylglycinamide ribonucleotide amidotransferase; FGAR amidotransferase; FGAR-ATEscherichia coli K-12
Guanylate kinaseEC 2.7.4.8; GMP kinaseEscherichia coli K-12
AmidophosphoribosyltransferaseATase; EC 2.4.2.14; Glutamine phosphoribosylpyrophosphate amidotransferase; GPATaseEscherichia coli K-12
Ribonucleoside-diphosphate reductase 2 subunit betaEC 1.17.4.1; R2F protein; Ribonucleotide reductase 2Escherichia coli K-12
Ribonucleoside-diphosphate reductase 2 subunit alphaEC 1.17.4.1; R1E protein; Ribonucleotide reductase 2Escherichia coli K-12
Ribonucleoside-diphosphate reductase 1 subunit betaEC 1.17.4.1; Protein B2; Protein R2; Ribonucleotide reductase 1Escherichia coli K-12
Phosphoribosylformylglycinamidine cyclo-ligaseEC 6.3.3.1; AIR synthase; AIRS; Phosphoribosyl-aminoimidazole synthetaseEscherichia coli K-12
GMP synthase [glutamine-hydrolyzing]EC 6.3.5.2; GMP synthetase; GMPS; Glutamine amidotransferaseEscherichia coli K-12
N5-carboxyaminoimidazole ribonucleotide synthaseN5-CAIR synthase; EC 6.3.4.18; 5-(carboxyamino)imidazole ribonucleotide synthetaseEscherichia coli K-12
Corrinoid adenosyltransferaseEC 2.5.1.17; Cob(II)alamin adenosyltransferase; Cob(II)yrinic acid a,c-diamide adenosyltransferase; Cobinamide/cobalamin adenosyltransferaseEscherichia coli K-12
ATP synthase epsilon chainATP synthase F1 sector epsilon subunit; F-ATPase epsilon subunitEscherichia coli K-12
Nucleoside diphosphate kinaseNDK; NDP kinase; EC 2.7.4.6; Nucleoside-2-P kinaseEscherichia coli K-12
Phosphoribosylaminoimidazole-succinocarboxamide synthaseEC 6.3.2.6; SAICAR synthetaseEscherichia coli K-12
ATP synthase subunit bATP synthase F(0) sector subunit b; ATPase subunit I; F-type ATPase subunit b; F-ATPase subunit bEscherichia coli K-12
ATP synthase subunit deltaATP synthase F(1) sector subunit delta; F-type ATPase subunit delta; F-ATPase subunit deltaEscherichia coli K-12
ATP synthase gamma chainATP synthase F1 sector gamma subunit; F-ATPase gamma subunitEscherichia coli K-12
ATP synthase subunit alphaEC 7.1.2.2; ATP synthase F1 sector subunit alpha; F-ATPase subunit alphaEscherichia coli K-12
ATP synthase subunit betaEC 7.1.2.2; ATP synthase F1 sector subunit beta; F-ATPase subunit betaEscherichia coli K-12
N5-carboxyaminoimidazole ribonucleotide mutaseN5-CAIR mutase; EC 5.4.99.18; 5-(carboxyamino)imidazole ribonucleotide mutaseEscherichia coli K-12
Bifunctional purine biosynthesis protein PurHEscherichia coli K-12
Phosphoribosylamine--glycine ligaseEC 6.3.4.13; GARS; Glycinamide ribonucleotide synthetase; Phosphoribosylglycinamide synthetaseEscherichia coli K-12
Anaerobic ribonucleoside-triphosphate reductaseEC 1.1.98.6; Class III ribonucleoside-triphosphate reductaseEscherichia coli K-12
Formate-dependent phosphoribosylglycinamide formyltransferase5'-phosphoribosylglycinamide transformylase 2; Formate-dependent GAR transformylase; 2.1.2.-; GAR transformylase 2; GART 2; Non-folate glycinamide ribonucleotide transformylase; Phosphoribosylglycinamide formyltransferase 2Escherichia coli K-12
ATP synthase subunit cATP synthase F(0) sector subunit c; Dicyclohexylcarbodiimide-binding protein; F-type ATPase subunit c; F-ATPase subunit c; Lipid-binding proteinEscherichia coli K-12

Compounds (25)

CompoundDescription
hydronium ion
Orthophosphate
glutamic acidA non-essential amino acid naturally occurring in the L-form. Glutamic acid is the most common excitatory neurotransmitter in the CENTRAL NERVOUS SYSTEM.
NADH
Adenosine TriphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
glutamineA non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from GLUTAMIC ACID and AMMONIA. It is the principal carrier of NITROGEN in the body and is an important energy source for many cells.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
adenosine monophosphateAdenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
phosphoribosyl pyrophosphateThe key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.
hydrogen carbonate
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Coenzyme A
adenylosuccinate
phosphoribosyl-N-formylglycineamide
triphosphate
NADA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
xanthosine 5'-triphosphateRN given refers to parent cpd
itaconic acid
saicaradenosylsuccinase catalyzes its conversion to AICAR
aminoimidazole ribotide
carboxyaminoimidazole ribotidereacts with alanosine to form antimetabolite; substrate for EC 4.1.1.21; structure in second source
5-formamidoimidazole-4-carboxamide ribotidepurine precursor
deoxyadenosine diphosphateRN given refers to parent cpd.
pyrophosphate
aica ribonucleotidepurine precursor that has antineoplastic activity
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