Page last updated: 2024-10-06

Peptidoglycan Biosynthesis II

Proteins (30)

ProteinSynonymsTaxonomy
Penicillin-binding protein 1BPBP-1b; PBP1b; Murein polymeraseEscherichia coli K-12
Peptidoglycan D,D-transpeptidase MrdAEC 3.4.16.4; Penicillin-binding protein 2; PBP-2Escherichia coli K-12
UDP-N-acetylglucosamine 1-carboxyvinyltransferaseEC 2.5.1.7; Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPTEscherichia coli K-12
Bifunctional protein GlmUEscherichia coli K-12
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferaseEC 2.4.1.227; Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferaseEscherichia coli K-12
Peptidoglycan D,D-transpeptidase FtsIEC 3.4.16.4; Essential cell division protein FtsI; Murein transpeptidase; Penicillin-binding protein 3; PBP-3; Peptidoglycan synthase FtsIEscherichia coli K-12
Penicillin-binding protein 1APBP-1a; PBP1aEscherichia coli K-12
D-alanine--D-alanine ligase BEC 6.3.2.4; D-Ala-D-Ala ligase B; D-alanylalanine synthetase BEscherichia coli K-12
Glutamate racemaseEC 5.1.1.3Escherichia coli K-12
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligaseEC 6.3.2.10; D-alanyl-D-alanine-adding enzyme; UDP-MurNAc-pentapeptide synthetaseEscherichia coli K-12
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligaseEC 6.3.2.13; Meso-A2pm-adding enzyme; Meso-diaminopimelate-adding enzyme; UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase; UDP-MurNAc-tripeptide synthetase; UDP-N-acetylmuramyl-tripeptide synthetaseEscherichia coli K-12
UDP-N-acetylenolpyruvoylglucosamine reductaseEC 1.3.1.98; UDP-N-acetylmuramate dehydrogenaseEscherichia coli K-12
Phospho-N-acetylmuramoyl-pentapeptide-transferaseEC 2.7.8.13; UDP-MurNAc-pentapeptide phosphotransferaseEscherichia coli K-12
Glucose-6-phosphate isomeraseGPI; EC 5.3.1.9; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHIEscherichia coli K-12
UDP-N-acetylmuramoylalanine--D-glutamate ligaseEC 6.3.2.9; D-glutamic acid-adding enzyme; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetaseEscherichia coli K-12
UDP-N-acetylmuramate--L-alanine ligaseEC 6.3.2.8; UDP-N-acetylmuramoyl-L-alanine synthetaseEscherichia coli K-12
Phosphocarrier protein HPrHistidine-containing proteinEscherichia coli K-12
Phosphoglucosamine mutaseEC 5.4.2.10Escherichia coli K-12
D-alanine--D-alanine ligase AEC 6.3.2.4; D-Ala-D-Ala ligase A; D-alanylalanine synthetase AEscherichia coli K-12
Probable peptidoglycan glycosyltransferase FtsWPGT; EC 2.4.1.129; Cell division protein FtsW; Cell wall polymerase; Lipid II flippase FtsW; Peptidoglycan polymerase; PG polymeraseEscherichia coli K-12
Sodium/glutamate symporterGlutamate permeaseEscherichia coli K-12
Lipid II flippase MurJPeptidoglycan biosynthesis protein MurJEscherichia coli K-12
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]EC 2.6.1.16; D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine--D-fructose-6-phosphate amidotransferaseEscherichia coli K-12
Proton/glutamate-aspartate symporterGlutamate-aspartate carrier protein; Proton-glutamate-aspartate transport proteinEscherichia coli K-12
Biosynthetic peptidoglycan transglycosylaseEC 2.4.1.129; Glycan polymerase; Monofunctional biosynthetic peptidoglycan transglycosylase; Monofunctional glycosyltransferase; Monofunctional GTase; Peptidoglycan glycosyltransferase MtgA; PGTEscherichia coli K-12
PTS system mannose-specific EIIAB componentEC 2.7.1.191; EIIAB-Man; EIII-ManEscherichia coli K-12
PTS system mannose-specific EIIC componentEII-P-Man; EIIC-Man; Mannose permease IIC componentEscherichia coli K-12
PTS system mannose-specific EIID componentEII-M-Man; EIID-Man; Mannose permease IID componentEscherichia coli K-12
Penicillin-binding protein 1CPBP-1c; PBP1cEscherichia coli K-12
D-serine/D-alanine/glycine transporterEscherichia coli O157:H7

Compounds (24)

CompoundDescription
hydronium ion
Orthophosphate
glutamic acidA non-essential amino acid naturally occurring in the L-form. Glutamic acid is the most common excitatory neurotransmitter in the CENTRAL NERVOUS SYSTEM.
Adenosine TriphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
glutamineA non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from GLUTAMIC ACID and AMMONIA. It is the principal carrier of NITROGEN in the body and is an important energy source for many cells.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
uridine monophosphate5'-Uridylic acid. A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
uridine diphosphateA uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.
uridine triphosphateUridine 5'-(tetrahydrogen triphosphate). A uracil nucleotide containing three phosphate groups esterified to the sugar moiety.
SodiumA member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23.
Coenzyme A
phosphoenolpyruvateA monocarboxylic acid anion derived from selective deprotonation of the carboxy group of phosphoenolpyruvic acid. It is a metabolic intermediate in GLYCOLYSIS; GLUCONEOGENESIS; and other pathways.
d-glutamate
lorglumideRN given refers to (+-)-isomer
glucosamine 6-phosphateRN given refers to parent cpd
n-acetylglucosamine-1-phosphatefound in proteinase I from Dictyostelium discoideum
Uridine Diphosphate N-AcetylglucosamineServes as the biological precursor of insect chitin, of muramic acid in bacterial cell walls, and of sialic acids in mammalian glycoproteins.
undecaprenyl pyrophosphate
alanylalanine, (D)-isomer
alanineA non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
uridine diphosphate n-acetylmuramic acidA nucleoside diphosphate sugar which is formed from UDP-N-acetylglucosamine and phosphoenolpyruvate. It serves as the building block upon which peptidoglycan is formed.
acetyl coenzyme aAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.
creolinfrom refined coal tar oils
pyrophosphate