Page last updated: 2024-10-06

PRC2 methylates histones and DNA

Proteins (9)

ProteinSynonymsTaxonomy
PHD finger protein 1Protein PHF1; hPHF1; Polycomb-like protein 1; hPCl1Homo sapiens (human)
PHD finger protein 19Polycomb-like protein 3; hPCL3Homo sapiens (human)
Polycomb protein EEDhEED; Embryonic ectoderm development protein; WD protein associating with integrin cytoplasmic tails 1; WAIT-1Homo sapiens (human)
Histone H4Homo sapiens (human)
Histone-lysine N-methyltransferase EZH2EC 2.1.1.356; ENX-1; Enhancer of zeste homolog 2; Lysine N-methyltransferase 6Homo sapiens (human)
Zinc finger protein AEBP2Adipocyte enhancer-binding protein 2; AE-binding protein 2Homo sapiens (human)
Polycomb protein SUZ12Chromatin precipitated E2F target 9 protein; ChET 9 protein; Joined to JAZF1 protein; Suppressor of zeste 12 protein homologHomo sapiens (human)
Metal-response element-binding transcription factor 2Metal regulatory transcription factor 2; Metal-response element DNA-binding protein M96; Polycomb-like protein 2; hPCl2Homo sapiens (human)
Protein JumonjiJumonji/ARID domain-containing protein 2Homo sapiens (human)

Compounds (1)

CompoundDescription
s-adenosylmethioninePhysiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)