Pathways > PI Metabolism
Page last updated: 2024-10-06

PI Metabolism

Proteins (49)

ProteinSynonymsTaxonomy
Patatin-like phospholipase domain-containing protein 6EC 3.1.1.5; Neuropathy target esteraseHomo sapiens (human)
Phosphatidylinositol 3-kinase regulatory subunit betaPI3-kinase regulatory subunit beta; PI3K regulatory subunit beta; PtdIns-3-kinase regulatory subunit beta; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta; PI3-kinase subunit p85-beta; PtdIns-3-kinase regulatory subunit p85-betaHomo sapiens (human)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformPI3-kinase subunit delta; PI3K-delta; PI3Kdelta; PtdIns-3-kinase subunit delta; EC 2.7.1.137; EC 2.7.1.153; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta; PtdIns-3-kinase subunit p110-delta; p110deltaHomo sapiens (human)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformPI3-kinase subunit alpha; PI3K-alpha; PI3Kalpha; PtdIns-3-kinase subunit alpha; EC 2.7.1.137; EC 2.7.1.153; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha; PtdIns-3-kinase subunit p110-alpha; p110alpha; Phosphoinositide 3-kHomo sapiens (human)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform PI3-kinase subunit gamma; PI3K-gamma; PI3Kgamma; PtdIns-3-kinase subunit gamma; EC 2.7.1.137; EC 2.7.1.153; EC 2.7.1.154; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma; PtdIns-3-kinase subunit p110-gamma; p110gamma; PhosphHomo sapiens (human)
Phosphatidylinositol 5-phosphate 4-kinase type-2 betaEC 2.7.1.149; 1-phosphatidylinositol 5-phosphate 4-kinase 2-beta; Diphosphoinositide kinase 2-beta; Phosphatidylinositol 5-phosphate 4-kinase type II beta; PI(5)P 4-kinase type II beta; PIP4KII-beta; PtdIns(5)P-4-kinase isoform 2-betaHomo sapiens (human)
Phosphatidylinositol 4-kinase betaPI4K-beta; PI4Kbeta; PtdIns 4-kinase beta; EC 2.7.1.67; NPIK; PI4K92; PI4KIIIHomo sapiens (human)
1-phosphatidylinositol 3-phosphate 5-kinasePhosphatidylinositol 3-phosphate 5-kinase; EC 2.7.1.150; FYVE finger-containing phosphoinositide kinase; PIKfyve; Phosphatidylinositol 3-phosphate 5-kinase type III; PIPkin-III; Type III PIP kinase; Serine-protein kinase PIKFYVE; 2.7.11.1Homo sapiens (human)
ADP-ribosylation factor 1Homo sapiens (human)
Glycerophosphocholine cholinephosphodiesterase ENPP6GPC-Cpde; EC 3.1.4.-; EC 3.1.4.38; Choline-specific glycerophosphodiester phosphodiesterase; Ectonucleotide pyrophosphatase/phosphodiesterase family member 6; E-NPP 6; NPP-6Homo sapiens (human)
Phosphatidylinositol 3-kinase regulatory subunit alphaPI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alphaHomo sapiens (human)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformPI3-kinase subunit beta; PI3K-beta; PI3Kbeta; PtdIns-3-kinase subunit beta; EC 2.7.1.153; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta; PtdIns-3-kinase subunit p110-beta; p110betaHomo sapiens (human)
Cytoplasmic tyrosine-protein kinase BMXEC 2.7.10.2; Bone marrow tyrosine kinase gene in chromosome X protein; Epithelial and endothelial tyrosine kinase; ETK; NTK38Homo sapiens (human)
Tyrosine-protein phosphatase non-receptor type 13EC 3.1.3.48; Fas-associated protein-tyrosine phosphatase 1; FAP-1; PTP-BAS; Protein-tyrosine phosphatase 1E; PTP-E1; hPTPE1; Protein-tyrosine phosphatase PTPL1Homo sapiens (human)
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTENEC 3.1.3.16; EC 3.1.3.48; EC 3.1.3.67; Mutated in multiple advanced cancers 1; Phosphatase and tensin homologHomo sapiens (human)
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alphaPI3K-C2-alpha; PtdIns-3-kinase C2 subunit alpha; EC 2.7.1.137; EC 2.7.1.153; EC 2.7.1.154; Phosphoinositide 3-kinase-C2-alphaHomo sapiens (human)
Phosphatidylinositol 5-phosphate 4-kinase type-2 alphaEC 2.7.1.149; 1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha; Diphosphoinositide kinase 2-alpha; PIP5KIII; Phosphatidylinositol 5-Phosphate 4-Kinase; PI5P4Kalpha; Phosphatidylinositol 5-phosphate 4-kinase type II alpha; PI(5)P 4-kinase type II alpha;Homo sapiens (human)
Phosphatidylinositol 5-phosphate 4-kinase type-2 gammaEC 2.7.1.149; Phosphatidylinositol 5-phosphate 4-kinase type II gamma; PI(5)P 4-kinase type II gamma; PIP4KII-gammaHomo sapiens (human)
Phosphoinositide 3-kinase regulatory subunit 5PI3-kinase regulatory subunit 5; PI3-kinase p101 subunit; Phosphatidylinositol 4,5-bisphosphate 3-kinase regulatory subunit; PtdIns-3-kinase regulatory subunit; Protein FOAP-2; PtdIns-3-kinase p101; p101-PI3KHomo sapiens (human)
Phosphatidylinositol 3-kinase regulatory subunit gammaPI3-kinase regulatory subunit gamma; PI3K regulatory subunit gamma; PtdIns-3-kinase regulatory subunit gamma; Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma; PI3-kinase subunit p55-gamma; PtdIns-3-kinase regulatory subunit p55-gamma; p55PIKHomo sapiens (human)
Pleckstrin homology domain-containing family A member 1PH domain-containing family A member 1; Tandem PH domain-containing protein 1; TAPP-1Homo sapiens (human)
Myotubularin-related protein 6Phosphatidylinositol-3,5-bisphosphate 3-phosphatase; 3.1.3.95; Phosphatidylinositol-3-phosphate phosphatase; 3.1.3.64Homo sapiens (human)
Polyphosphoinositide phosphataseEC 3.1.3.-; Phosphatidylinositol 3,5-bisphosphate 5-phosphatase; SAC domain-containing protein 3Homo sapiens (human)
Myotubularin-related protein 5Inactive phosphatidylinositol 3-phosphatase 5; SET-binding factor 1; Sbf1Homo sapiens (human)
Myotubularin-related protein 10Inactive phosphatidylinositol 3-phosphatase 10Homo sapiens (human)
Myotubularin-related protein 7Inositol 1,3-bisphosphate phosphatase; 3.1.3.-; Phosphatidylinositol-3-phosphate phosphatase; 3.1.3.64Homo sapiens (human)
Ras-related protein Rab-5AEC 3.6.5.2Homo sapiens (human)
Myotubularin-related protein 13Inactive phosphatidylinositol 3-phosphatase 13; SET-binding factor 2Homo sapiens (human)
Myotubularin-related protein 12Inactive phosphatidylinositol 3-phosphatase 12; Phosphatidylinositol 3 phosphate 3-phosphatase adapter subunit; 3-PAP; 3-phosphatase adapter proteinHomo sapiens (human)
Myotubularin-related protein 8Phosphatidylinositol-3,5-bisphosphate 3-phosphatase; 3.1.3.95; Phosphatidylinositol-3-phosphate phosphatase; 3.1.3.64Homo sapiens (human)
Ras-related protein Rab-4AHomo sapiens (human)
Phosphatidylinositol transfer protein beta isoformPI-TP-beta; PtdIns transfer protein beta; PtdInsTP betaHomo sapiens (human)
Ras-related protein Rab-14Homo sapiens (human)
ADP-ribosylation factor 3Homo sapiens (human)
Protein VAC14 homologTax1-binding protein 2Homo sapiens (human)
MyotubularinPhosphatidylinositol-3,5-bisphosphate 3-phosphatase; 3.1.3.95; Phosphatidylinositol-3-phosphate phosphatase; 3.1.3.64Homo sapiens (human)
Myotubularin-related protein 2Phosphatidylinositol-3,5-bisphosphate 3-phosphatase; 3.1.3.95; Phosphatidylinositol-3-phosphate phosphatase; 3.1.3.64Homo sapiens (human)
Phosphoinositide 3-kinase regulatory subunit 6Phosphoinositide 3-kinase gamma adapter protein of 87 kDa; p84 PI3K adapter protein; p84 PIKAP; p87 PI3K adapter protein; p87PIKAPHomo sapiens (human)
Patatin-like phospholipase domain-containing protein 7EC 3.1.1.-; EC 3.1.1.5Homo sapiens (human)
Lysophospholipase D GDPD3EC 3.1.4.-; Glycerophosphodiester phosphodiesterase 7; Glycerophosphodiester phosphodiesterase domain-containing protein 3Homo sapiens (human)
Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphataseType 1 PtdIns-4,5-P2 4-Ptase; EC 3.1.3.78; PtdIns-4,5-P2 4-Ptase I; Transmembrane protein 55BHomo sapiens (human)
Lysophospholipase D GDPD1EC 3.1.4.-; Glycerophosphodiester phosphodiesterase 4; Glycerophosphodiester phosphodiesterase domain-containing protein 1Homo sapiens (human)
Glycerophosphodiester phosphodiesterase domain-containing protein 5Glycerophosphocholine phosphodiesterase GDPD5; 3.1.4.2; Glycerophosphodiester phosphodiesterase 2; Phosphoinositide phospholipase C GDPD5; 3.1.4.11Homo sapiens (human)
Myotubularin-related protein 9Inactive phosphatidylinositol 3-phosphatase 9Homo sapiens (human)
RUN and FYVE domain-containing protein 1FYVE-finger protein EIP1; La-binding protein 1; Rab4-interacting protein; Zinc finger FYVE domain-containing protein 12Homo sapiens (human)
Pleckstrin homology domain-containing family A member 2PH domain-containing family A member 2; Tandem PH domain-containing protein 2; TAPP-2Homo sapiens (human)
Phosphatidylinositol-3-phosphatase SAC1EC 3.1.3.64; Phosphatidylinositol-4-phosphate phosphatase; Suppressor of actin mutations 1-like proteinHomo sapiens (human)
Glycerophosphodiester phosphodiesterase 1Glycerophosphoinositol glycerophosphodiesterase GDE1; 3.1.4.44; Lysophospholipase D GDE1; 3.1.4.-; Membrane-interacting protein of RGS16; RGS16-interacting membrane proteinHomo sapiens (human)
Phosphatidylinositide phosphatase SAC2EC 3.1.3.25; Inositol polyphosphate 5-phosphatase F; Sac domain-containing inositol phosphatase 2; Sac domain-containing phosphoinositide 4-phosphatase 2; hSAC2Homo sapiens (human)

Compounds (10)

CompoundDescription
phosphorylcholineCalcium and magnesium salts used therapeutically in hepatobiliary dysfunction.
cholineA basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.
Orthophosphate
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
inositolAn isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
guanosine triphosphateGuanosine 5'-(tetrahydrogen triphosphate). A guanine nucleotide containing three phosphate groups esterified to the sugar moiety.
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
alpha-glycerophosphoric acid
glycerylphosphorylcholineA component of PHOSPHATIDYLCHOLINES or LECITHINS, in which the two hydroxy groups of GLYCEROL are esterified with fatty acids. (From Stedman, 26th ed)
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