Page last updated: 2024-10-06

Oncogenic MAPK signaling

Proteins (36)

ProteinSynonymsTaxonomy
Fragile X mental retardation syndrome-related protein 1hFXR1pHomo sapiens (human)
Staphylococcal nuclease domain-containing protein 1EC 3.1.31.1; 100 kDa coactivator; EBNA2 coactivator p100; Tudor domain-containing protein 11; p100 co-activatorHomo sapiens (human)
RAF proto-oncogene serine/threonine-protein kinaseEC 2.7.11.1; Proto-oncogene c-RAF; cRaf; Raf-1Homo sapiens (human)
Serine/threonine-protein kinase B-rafEC 2.7.11.1; Proto-oncogene B-Raf; p94; v-Raf murine sarcoma viral oncogene homolog B1Homo sapiens (human)
MAP/microtubule affinity-regulating kinase 3EC 2.7.11.1; C-TAK1; cTAK1; Cdc25C-associated protein kinase 1; ELKL motif kinase 2; EMK-2; Protein kinase STK10; Ser/Thr protein kinase PAR-1; Par-1a; Serine/threonine-protein kinase p78Homo sapiens (human)
Dual specificity mitogen-activated protein kinase kinase 2MAP kinase kinase 2; MAPKK 2; EC 2.7.12.2; ERK activator kinase 2; MAPK/ERK kinase 2; MEK 2Homo sapiens (human)
Dual specificity mitogen-activated protein kinase kinase 1MAP kinase kinase 1; MAPKK 1; MKK1; EC 2.7.12.2; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1Homo sapiens (human)
Terminal nucleotidyltransferase 4ADNA polymerase sigma; LAK-1; Non-canonical poly(A) RNA polymerase PAPD7; 2.7.7.19; PAP-associated domain-containing protein 7; TRAMP-like complex polyadenylate polymerase; Terminal guanylyltransferase; 2.7.7.-; Terminal uridylyltransferase 5; TUTase 5; ToHomo sapiens (human)
Mitogen-activated protein kinase kinase kinase 11EC 2.7.11.25; Mixed lineage kinase 3; Src-homology 3 domain-containing proline-rich kinaseHomo sapiens (human)
Kinase suppressor of Ras 1EC 2.7.11.1Homo sapiens (human)
ProhibitinHomo sapiens (human)
Epithelial splicing regulatory protein 1RNA-binding motif protein 35A; RNA-binding protein 35AHomo sapiens (human)
Phosphatidylethanolamine-binding protein 1PEBP-1; HCNPpp; Neuropolypeptide h3; Prostatic-binding protein; Raf kinase inhibitor protein; RKIPHomo sapiens (human)
Acylglycerol kinase, mitochondrialhAGK; EC 2.7.1.107; EC 2.7.1.138; EC 2.7.1.94; Multiple substrate lipid kinase; HsMuLK; MuLK; Multi-substrate lipid kinaseHomo sapiens (human)
Bcl-2-like protein 11Bcl2-L-11; Bcl2-interacting mediator of cell deathHomo sapiens (human)
Ubiquitin-like modifier-activating enzyme ATG7ATG12-activating enzyme E1 ATG7; Autophagy-related protein 7; APG7-like; hAGP7; Ubiquitin-activating enzyme E1-like proteinHomo sapiens (human)
Lysine-specific demethylase 7AEC 1.14.11.-; JmjC domain-containing histone demethylation protein 1D; Lysine-specific demethylase 7Homo sapiens (human)
14-3-3 protein beta/alphaProtein 1054; Protein kinase C inhibitor protein 1; KCIP-1Homo sapiens (human)
Transcription intermediary factor 1-alphaTIF1-alpha; EC 2.3.2.27; E3 ubiquitin-protein ligase TRIM24; RING finger protein 82; RING-type E3 ubiquitin transferase TIF1-alpha; Tripartite motif-containing protein 24Homo sapiens (human)
Zinc finger CCCH-type antiviral protein 1ADP-ribosyltransferase diphtheria toxin-like 13; ARTD13; Inactive Poly [ADP-ribose] polymerase 13; PARP13; Zinc finger CCCH domain-containing protein 2; Zinc finger antiviral protein; ZAPHomo sapiens (human)
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1PAPS synthase 1; PAPSS 1; Sulfurylase kinase 1; SK 1; SK1Homo sapiens (human)
Ras-related protein M-RasEC 3.6.5.2; Ras-related protein R-Ras3Homo sapiens (human)
AP-3 complex subunit beta-1Adaptor protein complex AP-3 subunit beta-1; Adaptor-related protein complex 3 subunit beta-1; Beta-3A-adaptin; Clathrin assembly protein complex 3 beta-1 large chainHomo sapiens (human)
Prelamin-A/CHomo sapiens (human)
Chloride transport protein 6Chloride channel protein 6; ClC-6Homo sapiens (human)
Type-1 angiotensin II receptor-associated proteinAT1 receptor-associated proteinHomo sapiens (human)
Myosin phosphatase Rho-interacting proteinM-RIP; Rho-interacting protein 3; RIP3; p116RipHomo sapiens (human)
BRCA1-associated proteinEC 2.3.2.27; BRAP2; Impedes mitogenic signal propagation; IMP; RING finger protein 52; RING-type E3 ubiquitin transferase BRAP2; Renal carcinoma antigen NY-REN-63Homo sapiens (human)
Protein FAM131BHomo sapiens (human)
Angiogenic factor with G patch and FHA domains 1Angiogenic factor VG5Q; hVG5Q; G patch domain-containing protein 7; Vasculogenesis gene on 5q proteinHomo sapiens (human)
Protein quakingHqk; HqkIHomo sapiens (human)
A-kinase anchor protein 9AKAP-9; A-kinase anchor protein 350 kDa; AKAP 350; hgAKAP 350; A-kinase anchor protein 450 kDa; AKAP 450; AKAP 120-like protein; Centrosome- and Golgi-localized PKN-associated protein; CG-NAP; Protein hyperion; Protein kinase A-anchoring protein 9; PRKA9;Homo sapiens (human)
UPF0606 protein KIAA1549Homo sapiens (human)
Protein FAM114A2Homo sapiens (human)
Trafficking kinesin-binding protein 1106 kDa O-GlcNAc transferase-interacting protein; Protein MiltonHomo sapiens (human)
Leucine-rich repeat protein SHOC-2Protein soc-2 homolog; Protein sur-8 homologHomo sapiens (human)

Compounds (5)

CompoundDescription
Orthophosphate
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Guanosine MonophosphateA guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.