Page last updated: 2024-10-06

Glycolysis and Pyruvate Dehydrogenase

Proteins (24)

ProteinSynonymsTaxonomy
Fructose-bisphosphate aldolase class 2FBP aldolase; FBPA; EC 4.1.2.13; Fructose-1,6-bisphosphate aldolase; Fructose-bisphosphate aldolase class IIEscherichia coli K-12
Glucose-6-phosphate isomeraseGPI; EC 5.3.1.9; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHIEscherichia coli K-12
Fructose-bisphosphate aldolase class 1EC 4.1.2.13; Fructose-bisphosphate aldolase class I; FBP aldolaseEscherichia coli K-12
Pyruvate kinase IEC 2.7.1.40; PK-1Escherichia coli K-12
Pyruvate kinase IIEC 2.7.1.40; PK-2Escherichia coli K-12
Phosphocarrier protein HPrHistidine-containing proteinEscherichia coli K-12
Triosephosphate isomeraseTIM; TPI; EC 5.3.1.1; Triose-phosphate isomeraseEscherichia coli K-12
EnolaseEC 4.2.1.11; 2-phospho-D-glycerate hydro-lyase; 2-phosphoglycerate dehydrataseEscherichia coli K-12
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complexEC 2.3.1.12; Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; E2Escherichia coli K-12
ATP-dependent 6-phosphofructokinase isozyme 2ATP-PFK 2; Phosphofructokinase 2; EC 2.7.1.11; 6-phosphofructokinase isozyme II; Phosphohexokinase 2Escherichia coli K-12
ATP-dependent 6-phosphofructokinase isozyme 1ATP-PFK 1; Phosphofructokinase 1; EC 2.7.1.11; 6-phosphofructokinase isozyme I; Phosphohexokinase 1Escherichia coli K-12
2,3-bisphosphoglycerate-independent phosphoglycerate mutaseBPG-independent PGAM; Phosphoglyceromutase; iPGM; EC 5.4.2.12Escherichia coli K-12
Fructose-1,6-bisphosphatase class 1FBPase class 1; EC 3.1.3.11; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1Escherichia coli K-12
PTS system mannitol-specific EIICBA componentEIICBA-Mtl; EII-MtlEscherichia coli K-12
Mannitol-1-phosphate 5-dehydrogenaseEC 1.1.1.17Escherichia coli K-12
Phosphoglycerate kinaseEC 2.7.2.3Escherichia coli K-12
Glyceraldehyde-3-phosphate dehydrogenase AGAPDH-A; EC 1.2.1.12; NAD-dependent glyceraldehyde-3-phosphate dehydrogenaseEscherichia coli K-12
Fructose-1,6-bisphosphatase 1 class 2FBPase 1 class 2; EC 3.1.3.11; D-fructose-1,6-bisphosphate 1-phosphohydrolase 1 class 2Escherichia coli K-12
Fructose-1,6-bisphosphatase 2 class 2FBPase 2 class 2; EC 3.1.3.11; D-fructose-1,6-bisphosphate 1-phosphohydrolase 2 class 2Escherichia coli K-12
Pyridoxal phosphate phosphatase YbhAPLP phosphatase; EC 3.1.3.74Escherichia coli K-12
Phosphoenolpyruvate synthasePEP synthase; EC 2.7.9.2; Pyruvate, water dikinaseEscherichia coli K-12
2,3-bisphosphoglycerate-dependent phosphoglycerate mutaseBPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM; EC 5.4.2.11Escherichia coli K-12
PTS system glucose-specific EIIA componentEIIA-Glc; EIII-Glc; Glucose-specific phosphotransferase enzyme IIA componentEscherichia coli K-12
PTS system glucose-specific EIICB componentEIICB-Glc; EII-GlcEscherichia coli K-12

Compounds (23)

CompoundDescription
hydronium ion
pyruvic acidAn intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
Orthophosphate
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
NADH
Adenosine TriphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
adenosine monophosphateAdenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
mannitolA diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the body before any metabolism can take place. It can be used to treat oliguria associated with kidney failure or other manifestations of inadequate renal function and has been used for determination of glomerular filtration rate. Mannitol is also commonly used as a research tool in cell biological studies, usually to control osmolarity.
glucose, (beta-d)-isomer
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Coenzyme A
phosphoenolpyruvateA monocarboxylic acid anion derived from selective deprotonation of the carboxy group of phosphoenolpyruvic acid. It is a metabolic intermediate in GLYCOLYSIS; GLUCONEOGENESIS; and other pathways.
2-phosphoglycerate, (R)-isomer
NADA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
dihydroxyacetone phosphateAn important intermediate in lipid biosynthesis and in glycolysis.
glycerate 1,3-biphosphate
fructose-6-phosphateRN given refers to parent cpd with unspecified isomeric designation
3-phosphoglycerate
Glyceraldehyde 3-PhosphateAn aldotriose which is an important intermediate in glycolysis and in tryptophan biosynthesis.
mannitol-1-phosphate
acetyl coenzyme aAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.
dihydrolipoamideRN given refers to cpd without isomeric designation