Page last updated: 2024-10-06

FLT3 Signaling

Proteins (25)

ProteinSynonymsTaxonomy
Tyrosine-protein kinase LckEC 2.7.10.2; Leukocyte C-terminal Src kinase; LSK; Lymphocyte cell-specific protein-tyrosine kinase; Protein YT16; Proto-oncogene Lck; T cell-specific protein-tyrosine kinase; p56-LCKHomo sapiens (human)
Tyrosine-protein kinase FynEC 2.7.10.2; Proto-oncogene Syn; Proto-oncogene c-Fyn; Src-like kinase; SLK; p59-FynHomo sapiens (human)
Tyrosine-protein kinase HCKEC 2.7.10.2; Hematopoietic cell kinase; Hemopoietic cell kinase; p59-HCK/p60-HCK; p59Hck; p61HckHomo sapiens (human)
Receptor-type tyrosine-protein kinase FLT3EC 2.7.10.1; FL cytokine receptor; Fetal liver kinase-2; FLK-2; Fms-like tyrosine kinase 3; FLT-3; Stem cell tyrosine kinase 1; STK-1Homo sapiens (human)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformPI3-kinase subunit alpha; PI3K-alpha; PI3Kalpha; PtdIns-3-kinase subunit alpha; EC 2.7.1.137; EC 2.7.1.153; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha; PtdIns-3-kinase subunit p110-alpha; p110alpha; Phosphoinositide 3-kHomo sapiens (human)
Tyrosine-protein kinase SYKEC 2.7.10.2; Spleen tyrosine kinase; p72-SykHomo sapiens (human)
Tyrosine-protein phosphatase non-receptor type 11EC 3.1.3.48; Protein-tyrosine phosphatase 1D; PTP-1D; Protein-tyrosine phosphatase 2C; PTP-2C; SH-PTP2; SHP-2; Shp2; SH-PTP3Homo sapiens (human)
Phosphatidylinositol 3-kinase regulatory subunit alphaPI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alphaHomo sapiens (human)
Tyrosine-protein kinase CSKEC 2.7.10.2; C-Src kinase; Protein-tyrosine kinase CYLHomo sapiens (human)
Cyclin-dependent kinase inhibitor 1BCyclin-dependent kinase inhibitor p27; p27Kip1Homo sapiens (human)
Growth factor receptor-bound protein 10GRB10 adapter protein; Insulin receptor-binding protein Grb-IRHomo sapiens (human)
Receptor-type tyrosine-protein phosphatase etaProtein-tyrosine phosphatase eta; R-PTP-eta; EC 3.1.3.48; Density-enhanced phosphatase 1; DEP-1; HPTP eta; Protein-tyrosine phosphatase receptor type J; R-PTP-JHomo sapiens (human)
Forkhead box protein O3AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1Homo sapiens (human)
Son of sevenless homolog 1SOS-1Homo sapiens (human)
Bcl-2-like protein 11Bcl2-L-11; Bcl2-interacting mediator of cell deathHomo sapiens (human)
Tyrosine-protein kinase ABL2EC 2.7.10.2; Abelson murine leukemia viral oncogene homolog 2; Abelson tyrosine-protein kinase 2; Abelson-related gene protein; Tyrosine-protein kinase ARGHomo sapiens (human)
Src-like-adapter 2Modulator of antigen receptor signaling; MARS; Src-like adapter protein 2; SLAP-2Homo sapiens (human)
Suppressor of cytokine signaling 6SOCS-6; Cytokine-inducible SH2 protein 4; CIS-4; Suppressor of cytokine signaling 4; SOCS-4Homo sapiens (human)
SH2B adapter protein 3Lymphocyte adapter protein; Lymphocyte-specific adapter protein Lnk; Signal transduction protein LnkHomo sapiens (human)
GRB2-associated-binding protein 2GRB2-associated binder 2; Growth factor receptor bound protein 2-associated protein 2; pp100Homo sapiens (human)
Src-like-adapterSrc-like-adapter protein 1; SLAP-1; hSLAPHomo sapiens (human)
E3 ubiquitin-protein ligase CBLEC 2.3.2.27; Casitas B-lineage lymphoma proto-oncogene; Proto-oncogene c-Cbl; RING finger protein 55; RING-type E3 ubiquitin transferase CBL; Signal transduction protein CBLHomo sapiens (human)
Suppressor of cytokine signaling 2SOCS-2; Cytokine-inducible SH2 protein 2; CIS-2; STAT-induced STAT inhibitor 2; SSI-2Homo sapiens (human)
GRB2-related adapter protein 2Adapter protein GRID; GRB-2-like protein; GRB2L; GRBLG; GRBX; Grf40 adapter protein; Grf-40; Growth factor receptor-binding protein; Hematopoietic cell-associated adapter protein GrpL; P38; Protein GADS; SH3-SH2-SH3 adapter MonaHomo sapiens (human)
Fms-related tyrosine kinase 3 ligandFlt3 ligand; Flt3L; SL cytokineHomo sapiens (human)

Compounds (7)

CompoundDescription
Orthophosphate
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
Hydrogen PeroxideA strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Guanosine MonophosphateA guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
Guanosine DiphosphateA guanine nucleotide containing two phosphate groups esterified to the sugar moiety.
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.