way 123398 and sotalol
way 123398 has been researched along with sotalol in 2 studies
Compound Research Comparison
| Studies (way 123398) | Trials (way 123398) | Recent Studies (post-2010) (way 123398) | Studies (sotalol) | Trials (sotalol) | Recent Studies (post-2010) (sotalol) |
|---|---|---|---|---|---|
| 15 | 0 | 1 | 2,196 | 346 | 291 |
Protein Interaction Comparison
| Protein | Taxonomy | way 123398 (IC50) | sotalol (IC50) |
|---|---|---|---|
| Beta-2 adrenergic receptor | Homo sapiens (human) | 3.8169 | |
| Beta-1 adrenergic receptor | Homo sapiens (human) | 7.1087 | |
| Beta-3 adrenergic receptor | Homo sapiens (human) | 7.2 | |
| Beta-2 adrenergic receptor | Canis lupus familiaris (dog) | 5.0667 |
Research
Studies (2)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Colatsky, TJ; Parsons, RW; Spinelli, W | 1 |
| Colatsky, TJ; Moubarak, IF; Parsons, RW; Spinelli, W | 1 |
Other Studies
2 other study(ies) available for way 123398 and sotalol
| Article | Year |
|---|---|
Effects of WAY-123,398, a new class III antiarrhythmic agent, on cardiac refractoriness and ventricular fibrillation threshold in anesthetized dogs: a comparison with UK-68798, E-4031, and dl-sotalol.
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Atrioventricular Node; Benzimidazoles; Dogs; Electrocardiography; Electrophysiology; Female; Heart; Heart Conduction System; Hemodynamics; In Vitro Techniques; Male; Phenethylamines; Piperidines; Purkinje Fibers; Pyridines; Refractory Period, Electrophysiological; Sotalol; Sulfanilamides; Sulfonamides; Ventricular Fibrillation | 1992 |
Cellular electrophysiology of WAY-123,398, a new class III antiarrhythmic agent: specificity of IK block and lack of reverse use dependence in cat ventricular myocytes.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Benzimidazoles; Cats; Cells, Cultured; Culture Techniques; Dogs; Dose-Response Relationship, Drug; Myocardium; Phenethylamines; Piperidines; Potassium Channels; Purkinje Fibers; Pyridines; Sotalol; Sulfanilamides; Sulfonamides | 1993 |