vx-745 has been researched along with cyc 116 in 3 studies
| Studies (vx-745) | Trials (vx-745) | Recent Studies (post-2010) (vx-745) | Studies (cyc 116) | Trials (cyc 116) | Recent Studies (post-2010) (cyc 116) |
|---|---|---|---|---|---|
| 58 | 1 | 35 | 24 | 0 | 18 |
| Protein | Taxonomy | vx-745 (IC50) | cyc 116 (IC50) |
|---|---|---|---|
| Aurora kinase A | Homo sapiens (human) | 0.026 | |
| Cyclin-dependent kinase 4 | Homo sapiens (human) | 1.7 | |
| Cyclin-A2 | Homo sapiens (human) | 0.74 | |
| G1/S-specific cyclin-D1 | Homo sapiens (human) | 1.7 | |
| G1/S-specific cyclin-E1 | Homo sapiens (human) | 1.7 | |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | 1.22 | |
| Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | 0.069 | |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | 0.0566 | |
| Aurora kinase B | Homo sapiens (human) | 0.0141 | |
| Aurora kinase C | Homo sapiens (human) | 0.065 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hajduk, PJ; Johnson, EF; Kifle, L; Merta, PJ; Metz, JT; Soni, NB | 1 |
| Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ | 1 |
| Cahya, S; Cummins, DJ; Gao, C; Iversen, PW; Nicolaou, CA; Vieth, M; Wang, J; Watson, IA | 1 |
3 other study(ies) available for vx-745 and cyc 116
| Article | Year |
|---|---|
Navigating the kinome.
Topics: Drug Design; Pharmacogenetics; Protein Kinases; Proteome; Systems Biology | 2011 |
Identification of potent Yes1 kinase inhibitors using a library screening approach.
Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
Selectivity data: assessment, predictions, concordance, and implications.
Topics: Computer Simulation; Drug Discovery | 2013 |