Page last updated: 2024-09-02

st 587 and yohimbine

st 587 has been researched along with yohimbine in 8 studies

Compound Research Comparison

Studies
(st 587)
Trials
(st 587)
Recent Studies (post-2010)
(st 587)
Studies
(yohimbine)
Trials
(yohimbine)
Recent Studies (post-2010) (yohimbine)
67005,893253532

Protein Interaction Comparison

ProteinTaxonomyst 587 (IC50)yohimbine (IC50)
Alpha-2A adrenergic receptorHomo sapiens (human)0.0353
Cytochrome P450 2D6Homo sapiens (human)1.02
D(2) dopamine receptorHomo sapiens (human)2.06
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)1.3
Alpha-2B adrenergic receptorHomo sapiens (human)0.0428
Alpha-2C adrenergic receptorHomo sapiens (human)0.0466
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.126
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)0.0682
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)0.0682
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)0.0682
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)1.3
Alpha-1D adrenergic receptorHomo sapiens (human)1.013
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.126
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.074
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)1.3
5-hydroxytryptamine receptor 6Homo sapiens (human)1.689

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19908 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Batink, H; de Jonge, A; Thoolen, MJ; Timmermans, PB; van Zwieten, PA; Wilffert, B1
Badia, A; Sallés, J1
Czuczwar, SJ; Löscher, W1
Kubo, T; Misu, Y; Nagura, J1
Górka, Z; Rawłów, A1
Cooke, JP; Flavahan, NA; Rimele, TJ; Vanhoutte, PM1
de Jonge, A; Innemee, HC; Timmermans, PB; van Meel, JC; van Zwieten, PA1
Lues, I; Schümann, HJ1

Other Studies

8 other study(ies) available for st 587 and yohimbine

ArticleYear
Quantitative relationships between alpha-adrenergic activity and binding affinity of alpha-adrenoceptor agonists and antagonists.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood Pressure; Brain; Cell Membrane; Clonidine; Kinetics; Prazosin; Quinazolines; Rats; Receptors, Adrenergic, alpha; Structure-Activity Relationship; Vasoconstriction

1984
Effects of St-587 on the alpha-adrenoceptors in the bisected rat vas deferens.
    The Journal of pharmacy and pharmacology, 1989, Volume: 41, Issue:9

    Topics: Animals; Clonidine; Electric Stimulation; Epididymis; In Vitro Techniques; Male; Muscle, Smooth; Phenylephrine; Prazosin; Prostate; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vas Deferens; Yohimbine

1989
Comparison of drugs with different selectivity for central alpha 1-and alpha 2-adrenoceptors in animal models of epilepsy.
    Epilepsy research, 1987, Volume: 1, Issue:3

    Topics: Animals; Clonidine; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Epilepsy; Female; Gerbillinae; Kindling, Neurologic; Male; Mice; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Species Specificity; Yohimbine

1987
Pharmacological characterization of spinal alpha adrenoceptors related to blood pressure control in rats.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Azepines; Blood Pressure; Brain Stem; Clonidine; Dopamine; Guanabenz; Hydroxydopamines; Injections, Spinal; Male; Norepinephrine; Oxidopamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Spinal Cord; Yohimbine

1987
Involvement of postsynaptic alpha 1- and alpha 2-adrenoceptors in the flexor reflex activity in the spinal rats.
    Journal of neural transmission, 1986, Volume: 66, Issue:2

    Topics: Animals; Clonidine; Clozapine; Decerebrate State; Male; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Reflex; Spinal Cord; Yohimbine

1986
Characterization of postjunctional alpha-1 and alpha-2 adrenoceptors activated by exogenous or nerve-released norepinephrine in the canine saphenous vein.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 230, Issue:3

    Topics: Animals; Clonidine; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Female; Imidazoles; Male; Methoxamine; Norepinephrine; Phenoxybenzamine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Saphenous Vein; Sympathetic Nervous System; Tyramine; Yohimbine

1984
Differential effects of selective alpha 1- and alpha 2-adrenoceptor agonists on intraocular pressure in the conscious rabbit.
    Documenta ophthalmologica. Advances in ophthalmology, 1982, Jan-29, Volume: 52, Issue:3-4

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Clonidine; Female; Intraocular Pressure; Male; Phenylephrine; Procaine; Pupil; Yohimbine

1982
Effect of removing the endothelial cells on the reactivity of rat aortic segments to different alpha-adrenoceptor agonists.
    Naunyn-Schmiedeberg's archives of pharmacology, 1984, Volume: 328, Issue:2

    Topics: Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Azepines; Clonidine; Endothelium; Imidazoles; In Vitro Techniques; Male; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Rats; Rats, Inbred Strains; Xylazine; Yohimbine

1984