sibenadet has been researched along with cdp 840 in 1 studies
Studies (sibenadet) | Trials (sibenadet) | Recent Studies (post-2010) (sibenadet) | Studies (cdp 840) | Trials (cdp 840) | Recent Studies (post-2010) (cdp 840) |
---|---|---|---|---|---|
27 | 7 | 6 | 18 | 0 | 3 |
Protein | Taxonomy | sibenadet (IC50) | cdp 840 (IC50) |
---|---|---|---|
cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Rattus norvegicus (Norway rat) | 10 | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4C | Rattus norvegicus (Norway rat) | 10 | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Rattus norvegicus (Norway rat) | 10 | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4A | Homo sapiens (human) | 0.7675 | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4A | Rattus norvegicus (Norway rat) | 10 | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Homo sapiens (human) | 0.1028 | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4C | Homo sapiens (human) | 0.1032 | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Homo sapiens (human) | 0.1029 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (100.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Ball, RG; Blouin, M; Boulet, L; Côté, B; Ducharme, Y; Frenette, R; Friesen, RW; Girard, M; Girard, Y; Guay, D; Huang, Z; Jones, TR; Laliberté, F; Lynch, JJ; Mancini, J; Martins, E; Masson, P; Muise, E; Pon, DJ; Siegl, PK; Styhler, A; Tsou, NN; Turner, MJ; Young, RN | 1 |
1 other study(ies) available for sibenadet and cdp 840
Article | Year |
---|---|
Optimization of a tertiary alcohol series of phosphodiesterase-4 (PDE4) inhibitors: structure-activity relationship related to PDE4 inhibition and human ether-a-go-go related gene potassium channel binding affinity.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Alcohols; Animals; Bronchoconstriction; Crystallography, X-Ray; Cyclic N-Oxides; Cyclic Nucleotide Phosphodiesterases, Type 4; Dogs; Electrocardiography; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; Humans; In Vitro Techniques; Long QT Syndrome; Phosphodiesterase Inhibitors; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Binding; Pyridines; Rats; Saimiri; Sheep; Stereoisomerism; Structure-Activity Relationship; Tumor Necrosis Factor-alpha; Vomiting | 2003 |